Please use this identifier to cite or link to this item: https://repositorio.ufrn.br/jspui/handle/123456789/18983
Title: Astrocyte heterogeneity in the brain: from development to disease
Authors: Schitin, Clarissa
Nogaroli, Luciana
Costa, Marcos R.
Hedin-Pereira, Cecilia
Keywords: astrocyte;cerebral cortex;heterogeneity;progenitors;psychiatric diseases
Issue Date: 20-Mar-2015
Citation: SCHITINE, Clarissa; NOGAROLI, Luciana; COSTA, Marcos R.; HEDIN-PEREIRA, Cecilia. Astrocyte heterogeneity in the brain: from development to disease. Frontiers in Cellular Neuroscience. v. 9, mar. 2015. doi: 10.3389/fncel.2015.00076.
Abstract: In the last decades, astrocytes have risen from passive supporters of neuronal activity to central players in brain function and cognition. Likewise, the heterogeneity of astrocytes starts to become recognized in contrast to the homogeneous population previously predicted. In this review, we focused on astrocyte heterogeneity in terms of their morphological, protein expression and functional aspects, and debate in a historical perspective the diversity encountered in glial progenitors and how they may reflect mature astrocyte heterogeneity. We discussed data that show that different progenitors may have unsuspected roles in developmental processes. We have approached the functions of astrocyte subpopulations on the onset of psychiatric and neurological diseases.
URI: http://repositorio.ufrn.br:8080/jspui/handle/123456789/18983
ISSN: 1662-5102
Appears in Collections:ICe - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
Marcos Costa_ICE_2015_Astrocyte heterogeneity in the brain.pdfArtigo completo567,14 kBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.