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dc.contributor.authorSchitin, Clarissa-
dc.contributor.authorNogaroli, Luciana-
dc.contributor.authorCosta, Marcos R.-
dc.contributor.authorHedin-Pereira, Cecilia-
dc.identifier.citationSCHITINE, Clarissa; NOGAROLI, Luciana; COSTA, Marcos R.; HEDIN-PEREIRA, Cecilia. Astrocyte heterogeneity in the brain: from development to disease. Frontiers in Cellular Neuroscience. v. 9, mar. 2015. doi: 10.3389/fncel.2015.00076.pt_BR
dc.description.abstractIn the last decades, astrocytes have risen from passive supporters of neuronal activity to central players in brain function and cognition. Likewise, the heterogeneity of astrocytes starts to become recognized in contrast to the homogeneous population previously predicted. In this review, we focused on astrocyte heterogeneity in terms of their morphological, protein expression and functional aspects, and debate in a historical perspective the diversity encountered in glial progenitors and how they may reflect mature astrocyte heterogeneity. We discussed data that show that different progenitors may have unsuspected roles in developmental processes. We have approached the functions of astrocyte subpopulations on the onset of psychiatric and neurological diseases.pt_BR
dc.subjectcerebral cortexpt_BR
dc.subjectpsychiatric diseasespt_BR
dc.titleAstrocyte heterogeneity in the brain: from development to diseasept_BR
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