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Title: Project Pró-Natal: population-based study of perinatal and infant mortality in Natal, Northeast Brazil
Authors: Ramos, Ana Maria Oliveira
Maranhão, Técia Maria de Oliveira
Macedo, Albanita Leite Soares de
Pollock, Jon I.
Emond, Alan
Keywords: Infant mortality;Perinatal mortality;Autopsy;Malnutrition;Mortalidade infantil;Mortalidade perinatal;Autopsia;Desnutrição
Issue Date: 2000
Citation: RAMOS, A. M. O.; MARANHÃO, T. M. O.; MACEDO, A. L. S.; POLLOCK, J. I.; EMOND, A. (2000)
Abstract: The Pró-Natal project is a collaborative initiative that aims to improve maternal and infant health in a deprived community in Natal, Northeast Brazil. To assess the perinatal and infant mortality in this population of 40,000, we have collected over a 2-year period a consecutive series of 39 autopsy examinations on deaths under 1 year of age. During this period there were 2212 live births in the study population. The 14 perinatal deaths are described using theWrigglesworth classification, and the 25 infant deaths, using a clinicopathological system. The contribution of normally formed stillbirths was small (14%), which probably reflects the underreporting of stillbirths in this community. The most common cause of death in the live births was complications of prematurity (43%). Specific causes (22%) of perinatal deaths were predominantly infections, including one case of congenital syphilis. Perinatal asphyxia was diagnosed in 14%, and there was one case (7%) of a chromosome abnormality. Infant deaths were predominantly due to respiratory (45%) and gastrointestinal infections (28%), with chronic malnutrition as an underlying cause in 80% of cases. Prenatal care could theoretically have prevented three of the perinatal deaths, and a further six deaths could have been avoided by improved management of labor and the immediate neonatal period. Prevention of malnutrition and improved treatment of acute infections would contribute to a reduction in infant mortality in this population. The Pró-Natal project will use these data to design preventative interventions to reduce perinatal and infant mortality in this community
Description: RAMOS, Ana Maria de Oliveira et al. Project Pró-Natal: population-based study of perinatal and infant mortality in Natal, Northeast Brazil. Pediatric and Developmental Pathology, v.3, n.1, p.29-35, 2000
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