1. Universidade Federal do Rio Grande do Norte
2. Centro de Ciências da Saúde
3. DOD - Departamento de Odontologia
4. CCS - DOD - Artigos publicados em periódicos

Título:	Adenomatoid odontogenic tumor: retrospective study of 15 cases with emphasis on histopathologic features
Autor(es):	Matos, Felipe Rodrigues de Nonaka, Cassiano Francisco Weege Pinto, Leão Pereira Souza, Lelia Batista de Freitas, Roseana de Almeida
Palavras-chave:	Adenomatoid odontogenic tumor;Odontogenic tumor;Clinical;Histopathology
Data do documento:	2012
Referência:	MATOS, Felipe Rodrigues de et al. Adenomatoid Odontogenic Tumor: Retrospective Study of 15 Cases with Emphasis on Histopathologic Features. Head and Neck Pathology, v. 6, n. 4, p. 430-437, 2012.
Resumo:	Adenomatoid odontogenic tumor (AOT) is an uncommon benign epithelial lesion of odontogenic origin and, thus far, only few studies regarding the frequency of its many histopathologic features have been published in the literature. Thus, the aim of this study was to perform a retrospective analysis in a case series of AOT, with emphasis on the histopathological features. Fifteen cases of AOT were studied considering their clinical, radiographic and histopathologic aspects. Twelve cases affected females and the mean age was 16.2 years. The anterior maxilla was the most common site (66.6 %) and radiographically most cases showed a unilocular radiolucency with well-defined borders (57.1 %). Histologically, most cases exhibited predominantly a solid growth pattern (46.7 %) or a similar proportion of solid and cribriform patterns (46.7 %). Eosinophilic amorphous material ("tumor droplets") was found in all cases (100 %). Most tumors showed duct-like spaces (93.3 %) and convoluted structures (60.0 %) whereas a minor proportion of cases presented calcifying epithelial odontogenic tumor (CEOT)-like areas (26.7 %). Variable amounts of calcified material were found in most AOTs (80.0 %) whereas osteodentin and perivascular hyalinization were seen only rarely (6.7 % each one). Five (33.3 %) cases had areas mimicking a dentigerous cyst and most of these were diagnosed in females (80.0 %). Regarding the histopathologic features, our results suggest that AOTs usually show predominance of solid pattern or a similar proportion of solid and cribriform patterns while osteodentin and perivascular hyalinization are rarely seen in these tumors. In addition, areas mimicking a dentigerous cyst and CEOT-like areas are relatively infrequent findings in AOTs.
URI:	https://repositorio.ufrn.br/jspui/handle/123456789/21809
Aparece nas coleções:	CCS - DOD - Artigos publicados em periódicos

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