1. Universidade Federal do Rio Grande do Norte
2. Instituto do Cérebro
3. ICe - Artigos publicados em periódicos

Title:	SPLOOCE: A new portal for the analysis of human splicing variants
Authors:	Kroll, José Eduardo Galante, Pedro A. F. Ohara, Daniel T. Navarro, Fábio C. P. Ohno-Machado, Lucila Souza, Sandro José de
Keywords:	bioinformatics;alternative splicing;combined alternative splicing events;database;method of analysis;regular expressions;next-generation sequencing
Issue Date:	Nov-2012
Portuguese Abstract:	Understanding alternative splicing is crucial to elucidate the mechanisms behind several biological phenomena, including diseases. The huge amount of expressed sequences available nowadays represents an opportunity and a challenge to catalog and display alternative splicing events (ASEs). Although several groups have faced this challenge with relative success, we still lack a computational tool that uses a simple and straightforward method to retrieve, name and present ASEs. Here we present SPLOOCE , a portal for the analysis of human splicing variants. SPLOOCE uses a method based on regular expressions for retrieval of ASEs. We propose a simple syntax that is able to capture the complexity of ASEs.
URI:	https://repositorio.ufrn.br/jspui/handle/123456789/23275
ISSN:	1547-6286
Appears in Collections:	ICe - Artigos publicados em periódicos

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