Please use this identifier to cite or link to this item:
Title: Sleep deprivation effects on object discrimination task in zebrafish (Danio rerio)
Authors: Silva, Jaquelinne Pinheiro da
Silva, Priscila Fernandes
Nogueira, Marcelo Borges
Luchiari, Ana Carolina
Keywords: Sleep;Fish;Memory;Discrimination;Bayesian analysis
Issue Date: 19-Sep-2016
Citation: SILVA, Jaquelinne Pinheiro da; et al. Sleep deprivation effects on object discrimination task in zebrafish (Danio rerio). Animal Cognition, v. 20, p. 159-169, set. 2016. Disponível em:<>. Acesso em: 16 out. 2017.
Portuguese Abstract: The zebrafish is an ideal vertebrate model for neurobehavioral studies with translational relevance to humans. Many aspects of sleep have been studied, but we still do not understand how and why sleep deprivation alters behavioral and physiological processes. A number of hypotheses suggest its role in memory consolidation. In this respect, the aim of this study was to analyze the effects of sleep deprivation on memory in zebrafish (Danio rerio), using an object discrimination paradigm. Four treatments were tested: control, partial sleep deprivation, total sleep deprivation by light pulses, and total sleep deprivation by extended light. The control group explored the new object more than the known object, indicating clear discrimination. The partially sleep-deprived group explored the new object more than the other object in the discrimination phase, suggesting a certain degree of discriminative performance. By contrast, both total sleep deprivation groups equally explored all objects, regardless of their novelty. It seems that only one night of sleep deprivation is enough to affect discriminative response in zebrafish, indicating its negative impact on cognitive processes. We suggest that this study could be a useful screening tool for cognitive dysfunction and a better understanding of the effect of sleep-wake cycles on cognition
ISSN: 1435-9448
Appears in Collections:CB - DBIO - Artigos publicados em periódicos

Files in This Item:
File Description SizeFormat 
SleepDeprivationEffects_Silva_2016.pdf1.88 MBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.