1. Universidade Federal do Rio Grande do Norte
2. BDM - Biblioteca Digital de Monografias
3. Monografias de Graduação
4. CCS - TCC - Farmácia

Título:	Avaliação dos curativos à base de quitosana para feridas cutâneas: uma revisão
Título(s) alternativo(s):	Evaluation of chitosan-based dressings for cutaneous wounds: a review
Autor(es):	Silva, Lucas Gabriel de Medeiros da
Orientador:	Lima, Ádley Antonini Neves de
Palavras-chave:	polymeric dressings;skin wounds;chitosan;biological assays;wound healing;characterization techniques
Data do documento:	30-Jun-2022
Editor:	Universidade Federal do Rio Grande do Norte
Referência:	SILVA, Lucas Gabriel de Medeiros da. Evaluation of Chitosan-Based Dressings For Cutaneous Wounds: a Review. 2022. 36f. Trabalho de Conclusão de Curso (Graduação em Farmácia), Departamento de Farmácia, Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2022.
Resumo:	Biopolymeric dressings are increasingly being used as an effective alternative for wound healing, since they may present multifunctional properties such as biocompatibility, low toxicity, flexibility, permeability, easy removal and many others. Although there are several biopolymers for wound healing purposes, one of the most prominent is chitosan, known it for characteristics and potential for action, such as anti-inflammatory and antimicrobial. In this context, this article aimed to investigate in vitro and in vivo studies of chitosan dressings both isolated and in associations with other components. In in vitro studies, it was possible to evaluate parameters such as biocompatibility, antimicrobial activity and release assays, confirming positive results for chitosan dressings associated with other components. In in vivo studies, it was possible to evaluate the healing potential at macroscopic and histological levels. As main results, it was observed that the wounds showed complete healing rate between 9 and 14 days, complete re-epithelialization and collagen formation. Thus, this work revealed that it is possible to develop biopolymeric chitosan dressings incorporated to other polymers or active pharmaceutical inputs, since the results are extremely satisfactory, making it a promising strategy for clinical studies in the treatment of skin lesions.
URI:	https://repositorio.ufrn.br/handle/123456789/48627
Aparece nas coleções:	CCS - TCC - Farmácia

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