Manual farmacoterapêutico de medicamentos utilizados em pacientes pediátricos sob suporte ventilatório invasivo Natal/RN

Abstract

Orotracheal intubation is a procedure frequently performed in patients admitted to the pediatric intensive care unit. The purpose of this procedure is to initiate invasive mechanical ventilation and thus facilitate procedures; in addition to ensuring proper protection of a patient's airway. In pediatric hospitals, the rates of serious adverse events and non-serious adverse events are quite high. In the context of pediatric ICUs, the panorama of adverse events associated with tracheal intubation is quite similar, since the occurrence of events occurs with a certain frequency. This demonstrates the need for additional efforts to reduce them. Therefore, the objective of this work was to develop a pharmacotherapeutic manual of drugs used in pediatric patients under invasive ventilatory support in a teaching hospital. For the elaboration of the manual, pediatric guidelines and consensuses with a theme focused on invasive mechanical ventilation in pediatrics were taken into account. In addition, the selection of medications that would be present in this manual was obtained from a visualization of clinical practice associated with a dialogue with the care team that discriminated the list of medications usually used in patients under invasive mechanical ventilation. With this list in hand, a search was carried out in specialized literature in the field of pediatrics, as well as technical information available in medication package inserts for professionals, in addition to updated scientific articles in research databases (UptoDate and Micromedex). The manual contains the Common Brazilian Denomination (DCB), the commercial names of the drugs, standardized presentations available at the institution, pharmacological class, indications, minimum and maximum doses, administration routes, administration rates, diluents, diluent volume (including minimum volume for patients with water restriction), and those drugs that would have incompatibility in administration. Such information was arranged in topics (by ATC class), to facilitate handling by professionals. Therefore, it is hoped that now, after completing this manual, it will be able to assist in providing the most complete and safest assistance.