Accuracy of isolated nutrition indicators in diagnosing malnutrition and their prognostic value to predict death in patients with gastric and colorectal cancer: a prospective study

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dc.contributor.authorFayh, Ana Paula Trussardi
dc.contributor.authorSousa, Iasmin Matias de
dc.contributor.authorSilva, Flávia Moraes
dc.contributor.authorCarvalho, Ana Lucia Miranda de
dc.contributor.authorRocha, Ilanna Marques Gomes da
dc.date.accessioned2023-12-13T00:42:17Z
dc.date.available2023-12-13T00:42:17Z
dc.date.issued2021-05
dc.description.resumoBackground: The study aims to evaluate the accuracy of isolated nutrition indicators in diagnosing malnutrition in patients with gastric and colorectal cancer and their association with mortality. Methods: Prospective cohort study involving patients with cancer (n = 178) attending a reference center of oncology at any point in the disease trajectory or treatment. Nutrition status was evaluated in a unique moment by body mass index (BMI), PatientGenerated Subjective Global Assessment (PG-SGA), handgrip strength (HGS), and calf circumference (CC). Kappa coefficient, accuracy, sensitivity, specificity, positive and negative predictive values, and area under the receiver operating characteristic curve (AUC) were calculated for each nutrition indicator (PG-SGA as the reference method). The Cox proportional hazards model was used to assess hazard ratio (HR) and CI of mortality. Results: From the total patients, 11% were underweight, 48% were malnourished (PGSGA B or C), 43% had low HGS, and 55% presented low CC. There were 46 deaths (25.8%). BMI, HGS, and CC showed poor and fair agreements (κ < 0.30 for all ) and poor accuracy (AUC < 0.70 for all) in identifying malnutrition by PG-SGA. After the adjustment for confounders (age, treatment performed, site, and stage of cancer), PG-SGA (HR, 2.9; 95% CI, 1.5–5.9) and low CC (HR, 2.4; 95% CI, 1.1–5.2) were independent predictors of mortality. Conclusion: The nutrition indicators are not accurate in diagnosing malnutrition, whereas PG-SGA and low CC could predict mortality in gastric and colorectal cancer patients. Thus, CC should be combined with PG-SGA in nutrition assessmentspt_BR
dc.identifier.citationSOUSA, Iasmin Matias de; SILVA, Flávia Moraes; CARVALHO, Ana Lucia Miranda de; ROCHA, Ilanna Marques Gomes da; FAYH, Ana Paula Trussardi. Accuracy of isolated nutrition indicators in diagnosing malnutrition and their prognostic value to predict death in patients with gastric and colorectal cancer: a prospective study. Journal Of Parenteral And Enteral Nutrition, [S.l.], v. 46, n. 3, p. 508-516, 25 mai. 2021. DOI: 10.1002/jpen.2199. Disponível em: https://aspenjournals.onlinelibrary.wiley.com/doi/10.1002/jpen.2199. Acesso em 12 dez. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1002/jpen.2199
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/55833
dc.languageenpt_BR
dc.publisherJournal Of Parenteral And Enteral Nutritionpt_BR
dc.subjectAnthropometrypt_BR
dc.subjectnutrition assessmentpt_BR
dc.subjectnutrition statuspt_BR
dc.subjectoncologypt_BR
dc.subjectprognosispt_BR
dc.subjectsurvivalpt_BR
dc.titleAccuracy of isolated nutrition indicators in diagnosing malnutrition and their prognostic value to predict death in patients with gastric and colorectal cancer: a prospective studypt_BR
dc.typearticlept_BR

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