Histopathological prognosis of papillary thyroid carcinoma associated with nutritional status of vitamins A and E

Página do item simplificado Estatísticas
dc.contributor.authorLyra, Clélia de Oliveira
dc.contributor.authorAntoine, Lara Lima
dc.contributor.authorNeri, Julianna Lys de Sousa Alves
dc.contributor.authorMelo, Thaisa Cristina Tavares de
dc.contributor.authorLeite, Isabela Samária Fernandes
dc.contributor.authorSantos, Diego Marques da Costa
dc.contributor.authorAraújo, Jéssica Nayara Góes de
dc.contributor.authorSilva, Ana Gabriella da Costa Lemos
dc.contributor.authorAraújo, Nathália Kelly de
dc.contributor.authorRamos, Carlos César de Oliveira
dc.contributor.authorTarrapp, Sheila Ramos de Miranda Henriques
dc.contributor.authorLuchessi, André Ducati
dc.contributor.authorRibeira, Karla Danielly da Silva
dc.contributor.authorSilbiger, Vivian Nogueira
dc.date.accessioned2024-03-20T19:55:31Z
dc.date.available2024-03-20T19:55:31Z
dc.date.issued2021-07
dc.description.resumoBackground/Objectives: Experimental and clinical studies have shown that vitamins A and E can inhibit cancer formation and progression. The unfavourable status of these vitamins can represent risk factors for the disease. This study aimed to evaluate the associations between the nutritional status of vitamins A and E (serum levels and dietary intake) and histopathological outcomes in Papillary Thyroid Carcinoma (PTC) patients. Subjects/Methods: We applied a cross-sectional study (2017–2018) and quantified retinol (ROH) and α-tocopherol (TOH) serum levels and vitamins dietary intake of 46 PTC patients. Serum vitamins were quantified by high efficiency liquid chromatography and vitamins dietary intake was analyzed by 24‐hr dietary recalls. Results: Patients with lower ROH serum levels were more likely to present lymph node metastasis and/or angiolymphatic invasion (p = 0.025). In addition, higher vitamin A and vitamin E intake are related to the absence of extrathyroidal extension (p = 0.013) and lymph node metastasis (p = 0.007), respectively. Our findings suggest that a ROH serum level greater than 2.65 μmol/L in PTC patients may be a protective factor against the presence of lymph node metastasis and angiolymphatic invasion. In addition, vitamin A and E intake may protect against extrathyroidal extension and lymph node metastasis. Conclusions: A favourable nutritional status (higher serum levels and/or intake) of vitamin A and E may be associated with less aggressive tumours in PTC patientspt_BR
dc.identifier.citationANTOINE, Lara Lima; NERI, Julianna Lys de Sousa Alves; MELO, Thaisa Cristina Tavares de; LEITE, Isabela Samária Fernandes; SANTOS, Diego Marques da Costa; ARAÚJO, Jéssica Nayara Góes de; SILVA, Ana Gabriella da Costa Lemos; ARAÚJO, Nathália Kelly de; RAMOS, Carlos César de Oliveira; TARRAPP, Sheila Ramos de Miranda Henriques; LUCHESSI, André Ducati; LYRA, Clélia de Oliveira; RIBEIRO, Karla Danielly da Silva; SILBIGER; Vivian Nogueira. Histopathological prognosis of papillary thyroid carcinoma associated with nutritional status of vitamins A and E. European Journal Of Clinical Nutrition, [S.l.], v. 76, n. 3, p. 469-476, 6 jul. 2021. DOI: 10.1038/s41430-021-00976-5. Disponível em: https://www.nature.com/articles/s41430-021-00976-5. Acesso em: 11 mar. 2024.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1038/s41430-021-00976-5
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/57907
dc.languageenpt_BR
dc.publisherEuropean Journal of Clinical Nutritionpt_BR
dc.subjectPapillary Thyroid Carcinomapt_BR
dc.subjectPTCpt_BR
dc.subjectVitamin Apt_BR
dc.subjectVitamin Ept_BR
dc.subjectHistopathological Prognosipt_BR
dc.subjectNutritional Statuspt_BR
dc.titleHistopathological prognosis of papillary thyroid carcinoma associated with nutritional status of vitamins A and Ept_BR
dc.typearticlept_BR

Arquivos

Licença do Pacote

Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.45 KB
Formato:
Item-specific license agreed upon to submission
Nenhuma Miniatura disponível
Baixar

Coleções

CCS - DNUT - Artigos publicados em periódicos
Repositório Institucional - UFRN Campus Universitário Lagoa NovaCEP 59078-970 Caixa postal 1524 Natal/RN - BrasilUniversidade Federal do Rio Grande do Norte© Copyright 2025. Todos os direitos reservados.
Contato+55 (84) 3342-2260 - R232Setor de Repositórios Digitaisrepositorio@bczm.ufrn.br
DSpaceIBICT
OasisBR
LAReferencia
Customizado pela CAT - BCZM