Please use this identifier to cite or link to this item: https://repositorio.ufrn.br/jspui/handle/123456789/23321
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dc.contributor.authorKatche, Cynthia-
dc.contributor.authorDorman, Guido-
dc.contributor.authorSlipczuk, Leandro-
dc.contributor.authorCammarota, Martín-
dc.contributor.authorMedina, Jorge H.-
dc.date.accessioned2017-06-01T11:55:06Z-
dc.date.available2017-06-01T11:55:06Z-
dc.date.issued2013-
dc.identifier.urihttp://hdl.handle.net/123456789/23321-
dc.languageengpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectmemorypt_BR
dc.subjectcortical plasticitypt_BR
dc.subjectpost-training macromolecular synthesispt_BR
dc.subjectretrosplenial cortexpt_BR
dc.titleFunctional integrity of the retrosplenial cortex is essential for rapid consolidation and recall of fear memorypt_BR
dc.typearticlept_BR
dc.identifier.doi10.1101/lm.030080.112-
dc.description.resumoMemory storage is a temporally graded process involving different phases and different structures in the mammalian brain. Cortical plasticity is essential to store stable memories, but little is known regarding its involvement in memory processing. Here we show that fear memory consolidation requires early post-training macromolecular synthesis in the anterior part of the retrosplenial cortex (aRSC), and that reversible pharmacological inactivation of this cortical region impairs recall of recent as well as of remote memories. These results challenge the generally accepted idea that neocortical areas are slow encoding systems that participate in the retrieval of remote memories only.pt_BR
Appears in Collections:ICe - Artigos publicados em periódicos

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