1. Universidade Federal do Rio Grande do Norte
2. Instituto do Cérebro
3. ICe - Artigos publicados em periódicos

Título:	Shannon entropy of brain functional complex networks under the infuence of the psychedelic Ayahuasca
Autor(es):	Viol, A. Palhano-Fontes, Fernanda Onias, Heloisa Araújo, Dráulio Barros de Viswanathan, G. M.
Palavras-chave:	Ayahuasca;Shannon entropy;Psychedelic;fMRI
Data do documento:	7-Ago-2017
Resumo:	The entropic brain hypothesis holds that the key facts concerning psychedelics are partially explained in terms of increased entropy of the brain’s functional connectivity. Ayahuasca is a psychedelic beverage of Amazonian indigenous origin with legal status in Brazil in religious and scientific settings. In this context, we use tools and concepts from the theory of complex networks to analyze resting state fMRI data of the brains of human subjects under two distinct conditions: (i) under ordinary waking state and (ii) in an altered state of consciousness induced by ingestion of Ayahuasca. We report an increase in the Shannon entropy of the degree distribution of the networks subsequent to Ayahuasca ingestion. We also find increased local and decreased global network integration. Our results are broadly consistent with the entropic brain hypothesis. Finally, we discuss our findings in the context of descriptions of “mind-expansion” frequently seen in self-reports of users of psychedelic drugs.
URI:	https://repositorio.ufrn.br/jspui/handle/123456789/23825
Aparece nas coleções:	ICe - Artigos publicados em periódicos

Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.