Ferreira, Maria Angela FernandesLopes, Ana Karla Bezerra2017-03-072017-03-072016-09-27LOPES, Ana Karla Bezerra. A sífilis congênita nos municípios de grande porte do Brasil. 2016. 50f. Dissertação (Mestrado em Saúde Coletiva) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2016.https://repositorio.ufrn.br/jspui/handle/123456789/22154The Congenital Syphilis is characterized as infection of the conceptus, predominantly by transplacental transmission, from infected pregnant untreated or inadequately treated. In Brazil, the cities with more than 100,000 habitants, considered large cities, concentrated almost 80% of all reported cases of the disease. Thus, the objective of the study is to understand the distribution of congenital syphilis in cities with more than 100,000 habitants and assess its correlation with socioeconomic indicators and health services between 2007 and 2013. This is an ecological study and used as the unit of analysis the 283 Brazilian cities with more than 100,000 people. The study population consisted of all cases of congenital syphilis reported in the Notifiable Diseases Information System (SINAN) in these cities. Descriptive analysis of reported cases was performed, the bivariate analysis using Pearson's correlation coefficient to assess the degree of relationship of the prevalence of congenital syphilis with each of the 14 indicators selected for the study and cluster analysis was performed to group the municipalities according to their similarities and was performed Student's t-test to evaluate the difference between the groups. In the period from 2007 to 2013 were reported 38,533 cases of the disease in Brazil. Most of the cases consisted of children reported before 7 days of life, black, equally distributed between the sexes, mothers who underwent prenatal and were diagnosed in that period or at delivery. The northern and northeastern regions stood out for being the only ones with average prevalence above the national (2.54 / 1.000NV) in the period analyzed. Among the variables related to the quality and coverage of health services, the significant one was the percentage of live births variable with 7 or more prenatal consultations (r = -0.264). The IDHM (r = - 0.151), GINI index (r = 0.166), vulnerable percentage of poverty (r = 0.218), percentage of black women (r = 0.255), unemployment rate (r = 0.286), percentage of women 10 to 17 years with children (r = 0.256), Syphilis rate Gestational (r = 0.480) were significantly correlated. In the cluster analysis, two groups were generated (Group 1 and Group 2). On average, the detection rate of congenital syphilis in Group 1 was 1.45 (SD = 0.06) cases per thousand live births. Group 2, in turn, had an average of 5.11 (SD = 0.17) cases per thousand live births. The difference between them was significant t (275) = -20.21, p <0.001. Considering the results reaffirmed the importance of prenatal care in the face of congenital syphilis and the influence of socioeconomic factors in the rates presented by this disease.Acesso AbertoSífilis congênitaPré-natalPrevalênciaFatores socioeconômicosA sífilis congênita nos municípios de grande porte do BrasilmasterThesisCNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA