Souza, Dyego Leandro Bezerra deSousa, Gilmar Amorim dePessoa, Ranna SantosSouza Filho, Marlon César MeloOliveira, Daniel Fernandes MelloMedeiros, Luana LopesSouza, Dyeo Leandro BezerraCosta, Iris do Céu Clara2023-10-162023-10-162017SOUZA, Dyeo Leandro Bezerra; SOUSA, Gilmar Amorim de; PESSOA, Ranna Santos; SOUZA FILHO, Marlon César Melo; OLIVEIRA, Daniel Fernandes Mello; MEDEIROS, Luana Lopes; COSTA, Iris do Céu Clara. FACTORS ASSOCIATED WITH MORTALITY IN HEPATITIS C PATIENTS. Revista Ciência Plural, [S.L.], v. 2, n. 3, p. 45-58, 14 abr. 2017. Universidade Federal do Rio Grande do Norte - UFRN. http://dx.doi.org/10.21680/2446-7286.2016v2n3id11624. Disponível em: https://periodicos.ufrn.br/rcp/article/view/11624. Acesso em: 27 set. 2023.https://repositorio.ufrn.br/handle/123456789/54988Introduction:Hepatitis C still is the major responsible for progressive liver disease, which evolves to its chronic form in 80% of acutely infected patients, and can cause cirrhosis, digestive hemorrhage, liver failure, liver cancer, and death. Objective:Determine thefactors associated with death in hepatitis C patients. Methods:A detailed review was carried out in 10.304 medical records from the Liver Study Nucleus of the Onofre Lopes University Hospital, at the Federal University of Rio Grande do Norte (Northeast Brazil), between May 1995 and December 2013. Cases considered as suspect when the anti-HCV tested positive and confirmed when the qualitative RNA HCV tested positive (512 cases). Death was the dependent variable. The independent variables considered were: socio-demographic variables, variables associated with HCV infection, and those related to the progression of the disease. The association between independent variables and death was assessed, and the statistical significance (p) was calculated, along with OddsRatio (OR), and confidence intervals (95%). Results:The following associations were established with hepatitis C mortality: patients over the age of 35, treatment dropouts, diabetes mellitus, use of insulin, total bilirubin over 1.3 mg/dL, International Normalized Ratio at final consultation and low albumin at initial consultation (<3.5 g/dL), aspartate aminotransferase (AST), alanine aminotransferase (ALT), long prothrombin reaction time (PT), cirrhosis and liver carcinoma. Conclusion:The factor thatmost influences hepatitis C is the early diagnosis of the disease, before it progresses to cirrhosis and liver carcinoma. These patients must have easy access to health services, which should be guaranteed by public policies that are specifically defined for this purposehepatitis cchronic hepatitis cliver cirrhosispublic policiesHepatite Cpolíticas públicascirrose hepáticahepatite C crônicaarticlehttps://doi.org/10.21680/2446-7286.2016v2n3ID11624