Andrade, Vânia SousaSouza, Monalisa Silva de2018-12-182021-10-062018-12-182021-10-062018-11-22SOUZA, Monalisa Silva de. Prevalência microbiana das infecções oculares em pacientes atendidos no Hospital Universitário Onofre Lopes (HUOL-UFRN). 2018. 62 f. Monografia (Graduação em Biomedicina) – Curso de Biomedicina, Universidade Federal do Rio Grande do Norte, Natal, 2018.https://repositorio.ufrn.br/handle/123456789/43187The human eye is often susceptible to infections on its surface, either by imbalance of the normal microbiota or by the acquisition of exogenous microorganisms, as well as deficiency of the ocular immune system. The treatment of ocular lesions is currently based on the use of broad spectrum antimicrobials, but some species may acquire resistance, which makes it difficult to thwart these infections. The objective of this study was to perform a retrospective analysis of the individual data (age and gender) and the microbiological diagnosis of ocular infections in patients attended at the University Hospital Onofre Lopes in the period between 2016 and 2017. The prevalence of isolated agents, type of clinical specimen, as well as the analysis of the antimicrobial susceptibility profile used in the routine treatment of these infections. For this purpose, information on 190 patients was organized and compiled into a Microsoft® Office® Excel worksheet, and then subjected to statistical analysis using the Chi-square test. It was verified that the majority of the individuals who presented eye infections were in the age group 25 and 49 years, being the majority (65%) of the male gender. Among the microorganisms found, 58% were bacteria, and 42% fungi. Among the Gram-negative bacteria, the most prevalent were those of the genus Pseudomonas spp. found in 44.8% of bacterial infections. Among the filamentous fungi, the most prevalent was Fusarium spp, found in 90.5% of fungal infections. There was a significant association between Fusarium spp. and age range between 25 and 49 years (p = 0.01194). Among Gram-positive bacteria, the most prevalent was S. aureus, found in 17.2% of bacterial infections. The clinical specimen with the highest positivity in the cultures was corneal scraping representing (70%) of the cases. Regarding the antimicrobial susceptibility profile, most of the isolated bacteria were sensitive to the drugs used in ophthalmological practice, however, some of them, such as Pseudomonas spp., Coagulase negative Staphylococcus, Acinetobacter spp. and Enterobacter spp. were resistant. It is concluded that the ocular infections analyzed in the present study were caused by both bacteria and fungi, and the fungus Fusarium spp. the most prevalent agent, followed by Pseudomonas spp., and Staphylococcus aureus. Most of the pathogens isolated showed sensitivity to antimicrobial agents used in the routine treatment of ocular infections, but some of these agents were resistant. These results may contribute to the work of the professionals who work in the area, but it is necessary to include a greater number of variables, in order to allow a more detailed evaluation of the ocular pathologies.Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/Infecções ocularesPrevalência microbianaPerfil antimicrobianoEpidemiologiabachelorThesis