Mantello, Erika BarioniEvangelista, Alanna Stefany de Lima2021-10-142021-04-30EVANGELISTA, Alanna Stefany de Lima. Manifestações vestibulares em indivíduos com doenças do sistema nervoso central. 2021. 72f. Dissertação (Mestrado em Fonoaudiologia) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2021.https://repositorio.ufrn.br/handle/123456789/44573Introduction: Diseases of the central nervous system (CNS) affect the brain and spinal cord. CNS damage associated with vestibular symptoms occurs due to lesions in the central vestibular pathways. Objective: (1) To review the scientific literature on the applicability and results of the Video Head Impulse Test (vHIT) in diseases of the CNS. (2) To characterize the neurological and vestibular findings of clinical cases with Multiple Sclerosis (MS). Method: Dissertation structured in two articles. The first (1) is an integrative review of 18 scientific publications on the use of vHIT in individuals with CNS disease. The second (2) is the description of three clinical cases with MS. Results: (1) As for vHIT, the gain of the vestibulo-ocular reflex (VOR) was reduced in most studies, with the occurrence of compensatory saccades and described changes in oculomotor tests, such as the presence of spontaneous and semi-spontaneous nystagmus, in the visual VOR and VOR supression, in the saccade test and skew deviation test. (2) Vestibular symptoms and alterations were observed in at least one of the clinical tests of body balance and cerebellar function. In vHIT, alterations were obtained in oculomotor tests, such as the presence of semi-spontaneous nystagmus and in the latency and velocity parameters of the saccade test, and reduced gain in one or more vertical channels. The association of these findings suggests the presence of central vestibular dysfunction, compatible with the lesions detected in imaging exams. Conclusion: The findings of both studies provided evidence of changes in vestibular function and body balance in different neurological conditions.Acesso AbertoEquilíbrio corporalAvaliação vestibularDoenças do sistema nervoso centralmasterThesis