Rodrigues, Karla Danielly da Silva RibeiroMedeiros, Juliane Oliveira deRebouças, Amanda de SousaDimenstein, Roberto2024-11-272024-11-272022MEDEIROS, Juliane Oliveira de; REBOUÇAS, Amanda de Sousa; DIMENSTEIN, Roberto; RODRIGUES, Karla Danielly da Silva Ribeiro. Lipídeos totais e alfa-tocoferol no leite maduro: existe relação após suplementação com vitamina E? Demetra: Alimentação, Nutrição & Saúde, v. 17, n. 2, p. 1-10, 2022. DOI:http://dx.doi.org/10.12957/demetra.2022.65415. Disponível em: https://www.e-publicacoes.uerj.br/index.php/demetra/article/view/65415. Acesso em: 04 out. 2024.2176-9133https://repositorio.ufrn.br/handle/123456789/60691Fat intake during lactation may modify the concentration of vitamin E in human milk, probably because both nutrients are fat soluble and also share similar pathways of distribution, metabolism and molecular action. It is known that the high maternal vitamin E intake through supplementation alters alpha-tocopherol concentration in breast milk, but the relationship with human milk lipids has not yet been studied. Objective: This study aims to evaluate the association between alpha- tocopherol and total fat in breast milk after maternal supplementation with megadoses of vitamin E. Method: This study is part of a clinical trial composed of lactating women from a public outpatient clinic in the city of Natal, RN, Brasil. The group studied were 26 lactating women from a supplemented group whom were given a single dose of 800 IU of RRR-alpha-tocopherol (588 mg) between 30 and 90 days postpartum. Breast milk was collected before and 24h after supplementation. The food intake was assessed by a 24-hour Dietary Recall, the concentration of alpha-tocopherol was determined by high-performance liquid chromatography, and lipid concentration was determined by a creamatocrit analyzer. Results: All participants had inadequate vitamin intake (<16mg). Alpha-tocopherol concentration in milk increased from 294.8 μg/dL to 631.6 μg/dL after supplementation (p = 0.002). No relationship was found between alpha-tocopherol and total fat in breast milk before and after RRR- alpha-tocopherol supplementation. Conclusion: Therefore, vitamin E supplementation did not show a relationship between alpha-tocopherol and total fat in breast milk.Attribution 3.0 Brazilhttp://creativecommons.org/licenses/by/3.0/br/LactaçãoÁcidos GraxosConsumo AlimentarSuplementação Alimentararticle