Brandão, Deysiane OliveiraSilva, Vivian Hellen Tiburcio da2025-07-222025-07-222025-07-07SILVA, Vivian Hellen Tibúrcio da. Riscos cardiovasculares na população LGBT+: uma análise integrativa. 2025. 44 f. Monografia (Graduação em Biomedicina) – Universidade Federal do Rio Grande do Norte, Centro de Biociências, Natal, 2025.https://repositorio.ufrn.br/handle/123456789/64768Cardiovascular diseases remain one of the leading causes of morbidity and mortality worldwide, disproportionately affecting certain population groups. Among the most vulnerable is the LGBT population, whose continuous exposure to structural inequalities, institutional discrimination, and barriers to healthcare access exacerbates cardiovascular risk factors. This study aimed to investigate the specific cardiovascular risk factors affecting LGBT individuals, with an emphasis on clinical and laboratory findings. An integrative literature review was conducted, including articles published between 2005 and 2025 in databases such as PubMed, Scopus, Web of Science, SciELO, LILACS, and Google Scholar. The inclusion criteria comprised studies in Portuguese, English, and Spanish addressing social vulnerabilities, hormone therapy, psychosocial stress, and clinical-laboratory outcomes related to cardiovascular risk. The findings were categorized into five main themes: hematological alterations induced by hormone therapy; hepatic dysfunctions related to long-term hormone use; lipid and metabolic profiles in sexual minorities; stress and inflammation markers in contexts of discrimination; and limitations of traditional cardiovascular risk assessment tools, such as the Framingham score. Evidence showed that transgender individuals undergoing hormone therapy are at increased risk for thrombosis, polycythemia, and liver abnormalities. Sexual minorities showed higher prevalence of dyslipidemia, insulin resistance, hyperglycemia, and elevated levels of cortisol and C-reactive protein due to chronic psychosocial stress. Furthermore, traditional risk assessment tools were found to be inadequate for this population, as they overlook essential variables such as gender identity, hormone use, and psychosocial factors. It is concluded that there is an urgent need to update clinical and laboratory protocols to incorporate social determinants of health and address the specificities of the LGBT+ population. It is also recommended to strengthen professional training with an intersectional approach and to encourage further national studies focused on clinical biomarkers and hormone therapy in LGBT+ individuals.pt-BRAttribution 3.0 Brazilhttp://creativecommons.org/licenses/by/3.0/br/Saúde LBGT+Risco cardiovascularHormonioterapiaBiomarcadoresAnálises clínicasLGBT populationCardiovascular diseasesHormone therapyLaboratory biomarkersIntersectionalitybachelorThesis