Dantas, Rodrigo Assis NevesBarreto, Luciana Moreira Dantas2022-08-052022-08-052022-06-01BARRETO, Luciana Moreira Dantas. Qualidade na manipulação da terapia antineoplásica em um hospital universitário: implantação de um projeto de melhoria. 2022. 40f. Dissertação (Mestrado Profissional em Gestão da Qualidade em Serviços de Saúde) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2022.https://repositorio.ufrn.br/handle/123456789/49071Introduction: Improving the safety in the use of medicines, especially those with high risk, is the third Global Patient Safety Challenge, launched in 2017 by the World Health Organization (WHO). Antineoplastic drugs are part of the list of high risk drugs and therefore have a high potential to cause adverse events. The complexity of antineoplastic therapy (AT) contributes to the high error rate and severe severity. The present study has as its object the implementation of an improvement project in the AT manipulation process. Objectives: To evaluate the quality of the process of handling antineoplastic therapy in a university hospital in Rio Grande do Norte and to analyze the effect of a participatory intervention to improve this process. Methodology: This is the implementation of an improvement project, using a quasiexperimental before-after design, with a quantitative approach, carried out in an intravenous mixing center. Five quality criteria were developed to assess the handling of antineoplastic therapy, which were measured at three different times: an initial assessment and two post-intervention reassessments. The results of the intervention were submitted to statistical analysis and presented in a Pareto chart, to better demonstrate the level of quality achieved. Results: After the implementation of the interventions, there was an improvement in all the quality criteria of AT manipulation. Conclusion: The implementation of the improvement project proved to be effective, as it managed to improve the quality criteria addressed in this study and also caused a cultural change in the team, with a view to quality management in work processes.Acesso AbertoAntineoplásicosSegurança do pacienteBoas práticas de manipulaçãoGestão da qualidademasterThesisCNPQ::CIENCIAS DA SAUDE