Tinôco, Juliana DelgadoBezerra Filho, Luiz Carlos Xavier2025-07-222025-07-222025-07-10BEZERRA FILHO, Luiz Carlos Xavier. Espectrofotometria Uv-Visível aplicada à quantificação e validação analítica do ibuprofeno de sódio. 2025. 31 f. Trabalho de Conclusão de Curso (Graduação em Engenharia Ambiental) - Departamento de Engenharia Civil e Ambiental, Universidade Federal do Rio Grande do Norte, Natal, 2025.https://repositorio.ufrn.br/handle/123456789/64765The presence of pharmaceuticals in water bodies has become a growing concern in the environmental field due to their potential ecological risk and the difficulty of detecting them at low concentrations. Among these substances, ibuprofen stands out for its widespread use and frequent detection in aqueous matrices. This study aimed to validate an analytical method using UV-Visible spectrophotometry for the quantification of ibuprofen in aqueous solutions, also aiming to support future research related to the detection and monitoring of pharmaceuticals in the environment. Calibration curves were constructed in the range of 1 to 10 mg·L⁻¹, evaluating essential parameters such as precision, accuracy, detection limit (LD), and quantification limit (LQ). The method showed good precision from 4 mg·L⁻¹ onwards, with coefficients of variation below 10% at intermediate and higher concentrations, while higher variability was observed in the 1 to 3 mg·L⁻¹ range. LD and LQ values obtained using two different criteria ranged between 0.73 and 0.85 mg·L⁻¹ (LD) and between 2.19 and 2.57 mg·L⁻¹ (LQ), reinforcing the recommendation to use the method at concentrations above 4 mg·L⁻¹. However, its application in real environmental matrices requires further validation, particularly regarding selectivity in the presence of potential interferents.pt-BRemerging contaminantsspectrophotometric quantificationcalibration curvepharmaceuticals.Contaminantes emergentesQuantificação espectrofotométricaCurva de calibraçãoFármacos.bachelorThesisENGENHARIAS