Assunção, Isauremi Vieira deOliveira, Samila Neres de2017-09-152017-09-152017-07-10OLIVEIRA, Samila Neres de. Ibuprofeno e a associação de codeína + paracetamol frente a sensibilidade imediata no clareamento dentário: um ensaio clínico. 2017. 33f. Dissertação (Mestrado em Saúde Coletiva) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2017.https://repositorio.ufrn.br/jspui/handle/123456789/23928Sensitivity is the main adverse effect caused by tooth whitening. The aim of the present study was to compare the efficacy of ibuprofen and the combination of codeine + paracetamol in the control of the immediate sensitivity generated by dental office whitening with 35% hydrogen peroxide. Methods: Sixty volunteers were randomly selected and divided into three groups: Placebo (PL) 400 mg (n = 20), Ibuprofen (IB) 400 mg (n = 20) and Codeine 30 mg + Paracetamol 500 mg (N = 20). The volunteers were submitted to 2 bleaching sessions with 35% hydrogen peroxide in 2 applications of 20 min each. Medications were taken 1 hour before the bleaching procedure in both sessions. Sensitivity values were collected using a visual analog pain scale. Statistical analysis was done using ANOVA 1 Factor and post test of tukey, using Assistat® software. Results: There was a statistically significant difference between the treatments (p <0.01) (averages: PL: 4.7, IB: 4.8 and CP: 1.0). Conclusion: The treatment of codeine + paracetamol was more effective in eliminating the immediate sensitivity generated by tooth whitening with 35% hydrogen peroxide, with values close to zero, compared to ibuprofen and placebo.Acesso AbertoSensibilidade da dentinaClareamento dentárioPeróxido de hidrogêniomasterThesisCNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA