Morais, Danielle BarbosaSouza, Gabriel Ribeiro de2023-01-102023-01-102022-12-12SOUZA, Gabriel Ribeiro de. Desenvolvimento oocitário e embrionário de mulheres submetidas a tratamento de reprodução assistida e suas relações com a idade, hábitos de vida materno e fator masculino. 2022. 62 f. Trabalho de Conclusão de Curso (Graduação em Biomedicina) - Centro de Biociências. Universidade Federal do Rio Grande do Norte, 2022.https://repositorio.ufrn.br/handle/123456789/50900Infertility is a public health problem that affects many couples around the world. Numerous factors can change the quantity and quality of oocytes, as well the quality of the embryos produced in assisted human reproduction treatments, with emphasis on age and obesity in women, as well as the presence of infertility in men. Therefore, the aimed of this study was to carry out a descriptive, cross-sectional and retrospective observational analysis of the relationship between the oocyte and embryonic development of patients undergoing assisted reproduction treatment at the Assisted Reproduction Center of the Januário Cicco Maternity School (CRA/MEJC), Natal/ RN, between 2013 and 2018, with female age and life habits, as well with male factor of infertility. Regarding the age of the patients, significant correlations were found with the number of oocytes captured, mature and blastocysts. For the body mass index (BMI), the correlations were significative for the number of oocytes discarded and the cleavage rate. Together, age and BMI were statistically significant in predicting the number of grade 1 oocytes (germinal vesicle) and blastocysts. Regarding the presence of the male factor and its influence on embryonic development, significant differences were found in the number of blastocysts and positive beta-HCG indices. The results of this study suggest that a woman's age and lifestyle can negatively affect female fertility, compromising oocyte and embryonic development. When male factor of infertility is present, embryonic development is affected, reflecting a smaller number of embryos that reach the blastocyst stage and, consequently, lower levels of positive beta-HCG.Attribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/InfertilidadeReprodução humana assistidaOócitoQualidade embrionáriaÍndice de massa corporalInfertilidade masculinabachelorThesisCNPQ::CIENCIAS BIOLOGICAS::MORFOLOGIA::EMBRIOLOGIA