Jerônimo, Selma Maria BezerraBarreto, Sônia Maria de Medeiros2019-03-072019-03-072016-10-31BARRETO, Sônia Maria de Medeiros. Incidência de pré-eclâmpsia no Rio Grande do Norte e fatores de risco. 2016. 86f. Dissertação (Mestrado em Ciências da Saúde) - Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, 2016.https://repositorio.ufrn.br/jspui/handle/123456789/26674Hypertensive disorders of pregnancy are a group of illnesses that have high morbidity and mortality, both for the mother and the fetus. Environmental factors such as weight gain during pregnancy and infections appear to be associated with an increased risk of developing those diseases. Women more lower socioeconomic level have a higher risk of hypertensive disorders and their complications, including higher mortality. This study aimed to evaluate the incidence of hypertensive disorders of pregnancy (pre-eclampsia and eclampsia) in Brazil and in the state of Rio Grande do Norte, considering a time series, and to evaluate risk factors for disease, considering data from a reference center for high-risk pregnancy. Data were collected from the DATASUS from 2008 to 2014. The data of the reference service (Maternity Hospital Januário Cicco in Natal) were obtained for the period 2001 to 2014. The data for risk factors family were obtained through interviews with pregnant women. The incidence of hypertensive disorders of pregnancy was 3.9% for Brazil, while for the State of Rio Grande do Norte was 9.5% (p <0.05). In turn, the incidence of eclampsia was 0.4% in Brazil and 1.0% in the state of Rio Grande do Norte (p<0.05). The incidence of eclampsia has remained stationary in Brazil as a whole (p=0.560), and the state of Rio Grande do Norte, despite the magnesium sulfate use. Mortality due to hypertensive disease in Brazil was 0.48%, while mortality from eclampsia was 2.4%. Risk factors for preeclampsia in the state of Rio Grande do Norte included higher body mass index and maternal history of hypertension and preeclampsia. Family history of hypertension and pre-eclampsia indicates a genetic trend associated with risk of disease. In summary, hypertensive disorders of pregnancy remain an important health problem with implications for both women and children born of a preeclampsia pregnancy. There are preventable factors such as lower body mass index prior to pregnancy, weight control during pregnancy and better quality of the diet that decrease risk of hypertensive disorders of pregnancy and-or their complications.Acesso AbertoEpidemiologiaSíndrome HELLPPré-eclâmpsiaImunologiaCitocinasBrasilmasterThesisCNPQ::CIENCIAS DA SAUDE