Navegando por Autor "Aquino, Séphora Louyse Silva"
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Artigo Associations between components of metabolic Syndrome and demographic, nutritional, and lifestyle factors(Journal of Nutrition and Metabolism, 2024-01) Evangelista, Karine Cavalcanti Maurício de Sena; Lima, Layne Christina Benedito de Assis; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Peixoto, Talita do Nascimento; Lima, Severina Carla Vieira Cunha; Lima, Josivan Gomes; Pedrosa, Lucia Fátima CamposObjectives. To evaluate the associations between individuals with and without changes in components of metabolic syndrome (MetS) and demographic, nutritional, and lifestyle factors. Methods. A cross-sectional study was conducted with 224 individuals followed-up at a public hospital in Northeast Brazil. We used National Cholesterol Education Program-Adult Treatment Panel III (NCEP) criteria to diagnose MetS. We assessed components of MetS as dependent variables, while sex, age, food consumption, smoking, alcohol intake, physical activity, anthropometric parameters, and sleep hours were independent variables. Results. Comparing individuals with and without changes in components of MetS, the logistic regression models revealed that female sex was predictive of increased waist circumference and low HDL-c levels while advanced age was predictive of increased blood pressure and blood glucose levels. BMI emerged as a predictor for waist circumference and a protective factor for triglyceride levels. In addition, potassium intake, physical activity, and sleep duration were protective against decreased HDL-c, elevated triglyceride, and elevated blood pressure levels, respectively. Conclusion. Tis study demonstrated that sex, age, BMI, dietary potassium intake, physical activity, and hours of sleep are factors to be targeted in public health actions for prevention and treatment of MetSArtigo Associations between components of metabolic syndrome and demographic, nutritional, and lifestyle factors(Wiley, 2024) Lima, Severina Carla Vieira Cunha; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Peixoto, Talita do Nascimento; Lima, Layne Christina Benedito de Assis; Evangelista, Karine Cavalcanti Maurício Sena; Lima, Josivan Gomes; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0001-8268-1986Objectives. To evaluate the associations between individuals with and without changes in components of metabolic syndrome (MetS) and demographic, nutritional, and lifestyle factors. Methods. A cross-sectional study was conducted with 224 individuals followed-up at a public hospital in Northeast Brazil. We used National Cholesterol Education Program-Adult Treatment Panel III (NCEP) criteria to diagnose MetS. We assessed components of MetS as dependent variables, while sex, age, food consumption, smoking, alcohol intake, physical activity, anthropometric parameters, and sleep hours were independent variables. Results. Comparing individuals with and without changes in components of MetS, the logistic regression models revealed that female sex was predictive of increased waist circumference and low HDL-c levels while advanced age was predictive of increased blood pressure and blood glucose levels. BMI emerged as a predictor for waist circumference and a protective factor for triglyceride levels. In addition, potassium intake, physical activity, and sleep duration were protective against decreased HDL-c, elevated triglyceride, and elevated blood pressure levels, respectively. Conclusion. This study demonstrated that sex, age, BMI, dietary potassium intake, physical activity, and hours of sleep are factors to be targeted in public health actions for prevention and treatment of MetS.Artigo Effects of vitamin D supplementation on fasting glucose, dyslipidemia, blood pressure, and abdominal obesity among patients with metabolic syndrome: a protocol for systematic review and meta-analysis of randomized controlled trials(Systematic Reviews, 2020-08) Evangelista, Karine Cavalcanti Maurício de Sena; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira; Lima, Josivan Gomes; Oliveira, Antonio Gouveia; Cobucci, Ricardo Ney; Pedrosa, Lucia Fatima CamposBackground: Vitamin D deficiency can play a role in extraskeletal functions that are involved with a set of risk factors associated with metabolic syndrome (MetS). The purpose of this review is to investigate the impact of vitamin D supplementation on fasting glucose, dyslipidemia, blood pressure, and abdominal obesity among patients with MetS. Methods: EMBASE, Medline, Web of Science, Lilacs, the Cochrane Central Register of Controlled Trials, clinicaltrials.gov databases, and grey literature will be systematically searched for randomized controlled trials (RCTs) of vitamin D supplementation compared with placebo, through December 2020. We will include in the study patients with MetS diagnosed by the criteria set forth by the National Cholesterol Education Program Adult Treatment Panel III or the International Diabetes Federation. The effect of oral vitamin D supplementation on lipid profile improvement (triglycerides, high-density lipoprotein cholesterol—HDL-C) is this review’s primary outcome. The systematic review will be performed following the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) guidelines. The study screening, data extraction, and quality assessment will be fulfilled by two independent reviewers according to the Cochrane Risk of Bias tool (RoB 2.0). The results of the systematic review will be provided according to the type of intervention, characteristics of the target population, the methods of measurement of vitamin D, the calculated vitamin D concentrations, types of biological samples, and types of outcomes. Meta-analyses will be conducted where appropriate. The Cochran’s Q test and the I 2 -heterogeneity test will be used to assess the presence of heterogeneity and whether the fixed or the random-effects model would be appropriate for combining study results using the inverse variance method or the DerSimonian-Lair method, respectively. Publication bias will be evaluated using funnel plots and Egger’s and Begg’s tests. The strength of the evidence will be assessed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Discussion: This systematic review will assess the effects of vitamin D supplementation on fasting glucose and triglyceride levels, waist circumference and mean blood pressure, and HDL-C among individuals with MetS. These findings may assist with decision-making within a clinical settingArtigo Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study(Diabetology & Metabolic Syndrome, 2018-06) Fayh, Ana Paula Trussardi; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Pereira, Hermilla Torres; Freitas, Erika Paula Silva; Lima, Josivan Gomes; Lima, Severina Carla Vieira Cunha; Sena-Evangelista, Karine Cavalcanti Maurício; Pedrosa, Lucia Fátima CamposBackground: The risk of metabolic syndrome can be infuenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the infuence of environmental, biologi‑ cal, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome. Methods: This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years. The 25OHD concentration was considered the dependent variable; independent variables included age, sex, skin color, use of sunscreen, skin type, sun exposure score, ultraviolet radiation index, geographic location, season, body mass index, waist:hip ratio, waist circumference, parathyroid hormone level, total serum calcium level, and cal‑ cium and vitamin D intake. Results: The average vitamin D in individuals evaluated in summer 32±10 ng/mL was greater than in the winter 26±8 ng/mL (p<0.017). HDL-cholesterol was the only component of the MetS that difered signifcantly between the seasons (p<0.001), showing higher concentrations in autumn 45±8 mg/dL than in summer 35±8 mg/dL. In the multiple regression model, gender, WHR, sun exposure score, and winter vs. summer explained 10% of the variation in 25OHD concentration (p=0.004). Conclusions: Sex, waist:hip ratio, sun exposure, and summer season were predictors of 25OHD status among individuals with metabolic syndrome. HDL-cholesterol was the only component of metabolic syndrome that difered signifcantly between the seasons