Navegando por Autor "Lima, Diego Breno Soares de"

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Genital infection with herpes simplex virus types 1 and 2 in women from Natal, Brazil
(ISRN Obstetrics and Gynecology, 2014-03) Miranda, Cleine Aglacy Nunes; Lima, Érika Galvão; Lima, Diego Breno Soares de; Cobucci, Ricardo Ney Oliveira; Cornetta, Maria da Conceição de Mesquita; Fernandes, Thales Allyrio Araújo de Medeiros; Azevedo, Paulo Roberto Medeiros de; Azevedo, Jenner Chrystian Veríssimo de; Araújo, Josélio Maria Galvão de; Fernandes, José Veríssimo
Objective. To evaluate the prevalence of HSV-1 and HSV-2 in pregnant and nonpregnant women, testing the correlation between DNA of the viruses with colposcopic and/or cytological changes, and evaluate association with sociodemographic characteristics and sexual activity. Methods. Included in this study were 106 pregnant and 130 nonpregnant women treated at primary health care units ofNatal, Brazil, in the period 2010-2011.Thepatientswere examined by colposcopy, and two cervical specimenswere collected: one for cytology examination and another for analysis by PCR for detection ofHSV-1 and HSV-2. Results.HSV-1 alone was detected in 16.0% of pregnant and 30.0% of nonpregnant women. For HSV-2, these rates were 12.3% and 15.5%, respectively. HSV-2 had a higher correlation with cytology and/or colposcopy changes than HSV-1 did. Genital HSV-1 infection was not associated with any of the variables tested, whereas HSV-2 infection was associated with ethnicity, marital status, and number of sexual partners. Conclusions. The prevalence of HSV-1 was higher than that observed for HSV-2 in both pregnant and nonpregnant women. The genital infection by HSV-2 was higher in women with changed colposcopy and/or cytology, and it was associated with ethnicity, marital status, and number of sexual partners.
Genital tract infection with Chlamydia trachomatis in women attended at a cervical cancer screening program in Northeastern from Brazil
(Springer, 2014-10) Magalhães, Paulo André Freire; Miranda, Cleine Aglacy Nunes; Lima, Érika Galvão; Moizéis, Raíza Nara Cunha; Lima, Diego Breno Soares de; Cobucci, Ricardo Ney Oliveira; Fernandes, Thales Allyrio Araújo de Medeiros; Azevedo, Jenner Chrystian Veríssimo de; Azevedo, Paulo Roberto Medeiros de; Araújo, Josélio Maria Galvão de; Fernandes, José Veríssimo
Purpose This cross-sectional study aimed to estimate the prevalence of Chlamydia trachomatis (CT) infection alone and in combination with human papillomavirus (HPV). Furthermore, the study investigates whether the CT infection increases the risk of contracting HPV and whether the presence of both pathogens is associated with a higher prevalence of cervical lesions. Methods Cervical samples of 1,134 asymptomatic women enrolled in a screening program for cervical cancer were analyzed. Two cervical specimens were collected from each patient, one for cytologic examination and the other for detection of CT by polymerase chain reaction (PCR), using a primer pair which amplifies a specific sequence of the DNA plasmid. Results The overall prevalence rate infection was 10.9 %, being 10 % in the women with normal cytology, 13.8 % in those with atypical squamous cells of undetermined significance (ASC-US), and 25 % with low-grade squamous intraepithelial lesion (LSIL). The infection by CT did not increase the risk of acquiring HPV infection. The higher prevalence of LSIL in women co-infected with HPV and CT is possibly due to HPV. Conclusion CT infection was more prevalent in younger women aged up to 32 years, who had an early onset of reproductive activity and a history of having had multiple sexual partners lifelong may be at a greater risk of acquiring infection of the genital tract by C. trachomatis.
Knowledge about HPV and screening of cervical cancer among women from the metropolitan region of Natal, Brazil
(Hindawi Publishing Corporation, 2013-03) Lima, Érika Galvão; Lima, Diego Breno Soares de; Miranda, Cleine Aglacy Nunes; Pereira, Valeska Santana de Sena; Azevedo, Jenner Chrystian Veríssimo de; Araújo, Josélio Maria Galvão de; Fernandes, Thales Allyrio Araújo de Medeiros; Azevedo, Paulo Roberto Medeiros de; Fernandes, José Veríssimo
Objective. The purpose of this study was to assess the knowledge level about HPV and screening of cervical cancer in women from the metropolitan region of Natal, Brazil. Materials and Methods. A descriptive cross-sectional study involving sexually active women was conducted.Theparticipants were submitted to a face-to-face interview, using a structured questionnaire that permitted the quantification of data and opinions of the respondents. Results.Most participants (70.9%) had poor knowledge about HPV and also the Pap test (53.0%). The high level of knowledge about HPV was associated with age, education, marital status, household income, and pregnancy, while the high level of knowledge about the Pap test proved to be associated only with education and household income. Conclusion.The results highlight the need for performing educational campaigns emphasizing the role of HPV in the etiology of cervical lesions of different degrees, including cervical cancer, as well as the importance of having a Pap test regularly to prevent these diseases.
Prevalência da infecção pelo Papilomavírus humano, Chlamydia Trachomatis e Herpes Simples do tipo 2 em adolescentes atendidas em unidades de saúde pública de Natal
(Universidade Federal do Rio Grande do Norte, 2012-04-09) Lima, Diego Breno Soares de; Fernandes, José Veríssimo; ; http://lattes.cnpq.br/7078820975978056; ; http://lattes.cnpq.br/6007659058714923; Carvalho, Maria Goretti Freire de; ; http://lattes.cnpq.br/8934375314306198; Araújo, Joselio Maria Galvão de; ; http://lattes.cnpq.br/6430774978643765
O presente estudo avaliou o grau de conhecimento, atitude e prática do exame de Papanicolaou e do vírus do papiloma humano (HPV), além de analisar a prevalência da infecção genital por HPV, Herpes Simples tipo 2 (HSV-2) e Chlamydia trachomatis em adolescentes. O estudo constou de duas abordagens, uma baseada apenas em entrevistadas realizadas com adolescentes recrutadas em escolas públicas ou em unidades de saúde pública da cidade do Natal. A outra abordagem envolveu apenas um grupo de 132 adolescentes arroladas entre aquelas atendidas em duas unidades de saúde de Natal-RN. Das participantes deste segundo grupo foram coletados dois espécimes para análise laboratorial: um foi destinado à preparação de lâmina para o exame citológico de Papanicolaou, e outro processado para extração de DNA para análise molecular, visando à detecção de HPV, HSV-2 e da C. trachomatis. A presença do DNA dos três patógenos foi pesquisada por meio da técnica da reação em cadeia da polimerase (PCR). A presença de cada um dos três patógenos foi analisada em função das características sócio-demográficas, bem com da atividade sexual e reprodutiva visando identificar fatores de risco para a infecção e o desenvolvimento de lesões da cérvice uterina. Os resultados mostram que as adolescentes deste estudo apresentaram graus de conhecimento e de atitude muito baixos, tanto em relação ao exame citológico quanto ao HPV, embora tenham apresentado um percentual razoável de prática adequada do exame e da prevenção da infecção pelo HPV. A prevalência global da infecção pelo HPV foi de 54,5%, sendo 48,2% nas adolescentes com citologia normal e 86,4% naquelas com citologia alterada. Foi observada uma maior proporção de casos da infecção na faixa etária dos 18 aos 21. A prevalência da infecção pelo HPV foi ligeiramente maior entre as adolescentes grávidas. A prevalência global da infecção pelo HSV-2 foi de 13,6%, sendo 11,8% nas mulheres com citologia normal e 22,7% naquelas com citologia alterada. Uma maior proporção de casos da infecção foi encontrada na faixa etária dos 14 aos 17, sendo a prevalência ligeiramente maior entre as grávidas. A C. trachomatis foi encontrada com uma prevalência global de 19,7%, sendo 21,8% nas adolescentes com citologia normal e 9,1% naquelas com citologia alterada. A taxa de prevalecia foi maior na faixa etária dos 18 aos 21 anos e nas não grávidas

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Navegando por Autor "Lima, Diego Breno Soares de"