Navegando por Autor "Lima, Josivan Gomes"
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Artigo Analysis of testosterone pulsatility in women with ovulatory menstrual cycles(2009) Nóbrega, Lucia H. C.; Azevedo, George Dantas; Lima, Josivan Gomes; Ferriani, Rui Alberto; Sá, Marcos F. S; Maranhão, Técia Maria Oliveira; Spritzer, Poli MaraArtigo Associations between components of metabolic Syndrome and demographic, nutritional, and lifestyle factors(Journal of Nutrition and Metabolism, 2024-01) Evangelista, Karine Cavalcanti Maurício de Sena; Lima, Layne Christina Benedito de Assis; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Peixoto, Talita do Nascimento; Lima, Severina Carla Vieira Cunha; Lima, Josivan Gomes; Pedrosa, Lucia Fátima CamposObjectives. To evaluate the associations between individuals with and without changes in components of metabolic syndrome (MetS) and demographic, nutritional, and lifestyle factors. Methods. A cross-sectional study was conducted with 224 individuals followed-up at a public hospital in Northeast Brazil. We used National Cholesterol Education Program-Adult Treatment Panel III (NCEP) criteria to diagnose MetS. We assessed components of MetS as dependent variables, while sex, age, food consumption, smoking, alcohol intake, physical activity, anthropometric parameters, and sleep hours were independent variables. Results. Comparing individuals with and without changes in components of MetS, the logistic regression models revealed that female sex was predictive of increased waist circumference and low HDL-c levels while advanced age was predictive of increased blood pressure and blood glucose levels. BMI emerged as a predictor for waist circumference and a protective factor for triglyceride levels. In addition, potassium intake, physical activity, and sleep duration were protective against decreased HDL-c, elevated triglyceride, and elevated blood pressure levels, respectively. Conclusion. Tis study demonstrated that sex, age, BMI, dietary potassium intake, physical activity, and hours of sleep are factors to be targeted in public health actions for prevention and treatment of MetSArtigo Associations between components of metabolic syndrome and demographic, nutritional, and lifestyle factors(Wiley, 2024) Lima, Severina Carla Vieira Cunha; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Peixoto, Talita do Nascimento; Lima, Layne Christina Benedito de Assis; Evangelista, Karine Cavalcanti Maurício Sena; Lima, Josivan Gomes; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0001-8268-1986Objectives. To evaluate the associations between individuals with and without changes in components of metabolic syndrome (MetS) and demographic, nutritional, and lifestyle factors. Methods. A cross-sectional study was conducted with 224 individuals followed-up at a public hospital in Northeast Brazil. We used National Cholesterol Education Program-Adult Treatment Panel III (NCEP) criteria to diagnose MetS. We assessed components of MetS as dependent variables, while sex, age, food consumption, smoking, alcohol intake, physical activity, anthropometric parameters, and sleep hours were independent variables. Results. Comparing individuals with and without changes in components of MetS, the logistic regression models revealed that female sex was predictive of increased waist circumference and low HDL-c levels while advanced age was predictive of increased blood pressure and blood glucose levels. BMI emerged as a predictor for waist circumference and a protective factor for triglyceride levels. In addition, potassium intake, physical activity, and sleep duration were protective against decreased HDL-c, elevated triglyceride, and elevated blood pressure levels, respectively. Conclusion. This study demonstrated that sex, age, BMI, dietary potassium intake, physical activity, and hours of sleep are factors to be targeted in public health actions for prevention and treatment of MetS.Artigo Can body mass index identify cardiac autonomic dysfunction in women who are apparently healthy?(2019-05) Soares, Fabiano Henrique Rodrigues; Furstenberger, Alexandra Braga; Carvalho, Layssa Carolinne de Sousa; Melo, Melissa Yolanda Soares; Lima, Josivan Gomes; Sousa, Maria Bernardete Cordeiro deWe investigated the extent to which obesity could identify autonomic dysfunction of heart control in a cross-sectional study with 65 women (aged 18-45 years), categorized as eutrophic, overweight or obese. We collected anthropometric measures and measures of heart rate variability (HRV) between March 2015 and March 2017. Low frequency in normalized units (LF(nu)) over 46 was considered a marker of autonomic imbalance and high frequency in normalized units (HF(nu)) below 38 a marker of depressed vagal modulation. Overweight (mean difference MΔHF(nu) = -13.11 [95% confidence interval (CI) of difference, -25.88, -0.34], Hedges's g = 0.65, common language effect size (CL) = 68.1%) and obese (MΔHF(nu) = -21.22 [95% CI, -31.89, -10.55], Hedges's g = 1.17, CL = 79.2%) women presented depressed vagal modulation compared to eutrophic women. Autonomic imbalance increased as body mass index increased (eutrophic-to-overweight MΔLF(nu) = 13.06 [95% CI, 1.65, 24.47], g = 0.65, CL = 67.9%, and overweight-to-obese MΔLF(nu) = 21.07 [95% CI, 10.32, 31.82], g = 1.15, CL 78.9%). The odds ratio for depressed HF(nu) among overweight women was 2.36 (95% CI 0.77, 7.29) and 2.18 among obese women (95% CI 0.79, 5.99), as well as 9.17 (95% CI 2.62, 32.04) and 17.39 for increased LF(nu) (95% CI 2.13, 141.76), respectively. The parasympathetic activity is diminished and autonomic imbalance of the cardiac control increased with increasing BMI categories.Artigo Consumo de sódio em indivíduos com síndrome metabólica: um estudo baseado no teor de sódio da dieta e alimentos-fonte(Demetra, 2018) Lima, Severina Carla Vieira Cunha; Carvalho, Giovanna Melo de; Soares, Jainara da Silva; Freitas, Erika Paula Silva; Lima, Josivan Gomes; Evangelista, Karine Cavalcanti Maurício Sena; https://orcid.org/0000-0001-8268-1986Objetivo: Avaliar a ingestão energética e identificar o consumo de sódio e suas principais fontes em indivíduos com síndrome metabólica. Metodologia: Estudo tipo transversal realizado com 88 indivíduos com diagnóstico de síndrome metabólica, de ambos os sexos, adultos e idosos atendidos no Ambulatório de Endocrinologia do Hospital Universitário Onofre Lopes, Natal, RN. O consumo de energia, sódio e respectivos alimentos-fonte foram avaliados por meio de dois recordatórios de 24 horas, cuja análise foi realizada no Virtual Nutri Plus®. Resultados e discussão:A população estudada era predominantemente feminina (72,7%), com média de idade de 49,0 (11,3) anos. As comorbidades mais frequentes foram dislipidemia (92,0%) e hipertensão arterial (76,1%). Observou-se ingestão energética média de 1.664,4 (630,8) kcal/d e consumo médio de sódio de 2.792,8 (866,2) mg/d, registrando-se 82,2% dos indivíduos com ingestão acima do recomendado. Diferenças estatísticas significativas foram encontradas para ingestão energética entre os sexos (p<0,001), mas não para consumo de sódio (p=0,107). A utilização do sal de adição foi bastante expressiva na análise do consumo alimentar dessa população (310 repetições, correspondendo a uma média de 635,5mg de sódio). Alimentos industrializados foram os que apresentaram maior quantidade de sódio entre os alimentos consumidos, apesar de registrarmos poucos indivíduos fazendo uso desses produtos. Conclusão: A ingestão inadequada de sódio foi registrada em um percentual expressivo da população, podendo ter impacto negativo na saúde desses indivíduos, especialmente aqueles que convivem com hipertensão, evidenciando a necessidade de uma ação de educação nutricional mais ampla direcionada especificamente para essa população.Palavras-chave: Síndrome metabólica. Dieta hipossódica. Hipertensão. Consumo de alimentos.Artigo Consumo de sódio em indivíduos com síndrome metabólica: um estudo baseado no teor de sódio da dieta e alimentos-fonte(Demetra: Alimentação, Nutrição & Saúde, 2018-12) Evangelista, Karine Cavalcanti Maurício de Sena; Carvalho, Giovanna Melo de; Soares, Jainara da Silva; Freitas, Erika Paula Silva; Lima, Josivan Gomes; Lima, Severina Carla Vieira CunhaObjetivo: Avaliar a ingestão energética e identificar o consumo de sódio e suas principais fontes em indivíduos com síndrome metabólica. Metodologia: Estudo tipo transversal realizado com 88 indivíduos com diagnóstico de síndrome metabólica, de ambos os sexos, adultos e idosos atendidos no Ambulatório de Endocrinologia do Hospital Universitário Onofre Lopes, Natal, RN. O consumo de energia, sódio e respectivos alimentos-fonte foram avaliados por meio de dois recordatórios de 24 horas, cuja análise foi realizada no Virtual Nutri Plus®. Resultados e discussão: A população estudada era predominantemente feminina (72,7%), com média de idade de 49,0 (11,3) anos. As comorbidades mais frequentes foram dislipidemia (92,0%) e hipertensão arterial (76,1%). Observou-se ingestão energética média de 1.664,4 (630,8) kcal/d e consumo médio de sódio de 2.792,8 (866,2) mg/d, registrando-se 82,2% dos indivíduos com ingestão acima do recomendado. Diferenças estatísticas significativas foram encontradas para ingestão energética entre os sexos (p<0,001), mas não para consumo de sódio (p=0,107). A utilização do sal de adição foi bastante expressiva na análise do consumo alimentar dessa população (310 repetições, correspondendo a uma média de 635,5mg de sódio). Alimentos industrializados foram os que apresentaram maior quantidade de sódio entre os alimentos consumidos, apesar de registrarmos poucos indivíduos fazendo uso desses produtos. Conclusão: A ingestão inadequada de sódio foi registrada em um percentual expressivo da população, podendo ter impacto negativo na saúde desses indivíduos, especialmente aqueles que convivem com hipertensão, evidenciando a necessidade de uma ação de educação nutricional mais ampla direcionada especificamente para essa populaçãoArtigo Effects of vitamin D supplementation on cardiometabolic parameters among patients with metabolic syndrome: a systematic review and grade evidence synthesis of randomized controlled trials(Heliyon, 2023-11) Evangelista, Karine Cavalcanti Maurício de Sena; Aquino, Séphora; Cunha, Aline; Lima, Josivan Gomes; Oliveira, Antonio Gouveia; Cobucci, Ricardo Ney; Pedrosa, Lucia Fatima CamposVarious pathophysiologic mechanisms were proposed to underlie the effect of vitamin D on MetS components. In this systematic review, we reviewed randomized control clinical trials to verify whether vitamin D supplementation (VDS) at different doses is effective concomitantly in controlling high-density lipoprotein cholesterol (HDL-c), triglycerides (TG), fasting glucose level, blood pressure, and central obesity in adults diagnosed with MetS. The following scientific databases were searched from 1998 until April 2023: EMBASE, MEDLINE (PubMed), Web of Science, Latin American and Caribbean Health Sciences Literature (Lilacs), the Cochrane Central Register of Controlled Trials, clinicaltrial.gov, and Google Scholar. No language restrictions were applied. Seven studies were included, and they showed a high level of heterogeneity. All studies reported a significant increase in serum 25(OH)D levels in the intervention groups. Of these, only two noted a significant decrease in triglyceride (TG) level and waist circumference. However, the certainty levels of the evidence rating were very low and low for triglyceride (TG) level and waist circumference, respectively, and moderate for fasting glucose level, blood pressure, and HDL-c. In conclusion, despite these benefits, considering the low certainty, the evidence does not support that VDS decreases triglyceride (TG) level and waist circumference in adults with MetSArtigo Effects of vitamin D supplementation on fasting glucose, dyslipidemia, blood pressure, and abdominal obesity among patients with metabolic syndrome: a protocol for systematic review and meta-analysis of randomized controlled trials(Systematic Reviews, 2020-08) Evangelista, Karine Cavalcanti Maurício de Sena; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira; Lima, Josivan Gomes; Oliveira, Antonio Gouveia; Cobucci, Ricardo Ney; Pedrosa, Lucia Fatima CamposBackground: Vitamin D deficiency can play a role in extraskeletal functions that are involved with a set of risk factors associated with metabolic syndrome (MetS). The purpose of this review is to investigate the impact of vitamin D supplementation on fasting glucose, dyslipidemia, blood pressure, and abdominal obesity among patients with MetS. Methods: EMBASE, Medline, Web of Science, Lilacs, the Cochrane Central Register of Controlled Trials, clinicaltrials.gov databases, and grey literature will be systematically searched for randomized controlled trials (RCTs) of vitamin D supplementation compared with placebo, through December 2020. We will include in the study patients with MetS diagnosed by the criteria set forth by the National Cholesterol Education Program Adult Treatment Panel III or the International Diabetes Federation. The effect of oral vitamin D supplementation on lipid profile improvement (triglycerides, high-density lipoprotein cholesterol—HDL-C) is this review’s primary outcome. The systematic review will be performed following the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) guidelines. The study screening, data extraction, and quality assessment will be fulfilled by two independent reviewers according to the Cochrane Risk of Bias tool (RoB 2.0). The results of the systematic review will be provided according to the type of intervention, characteristics of the target population, the methods of measurement of vitamin D, the calculated vitamin D concentrations, types of biological samples, and types of outcomes. Meta-analyses will be conducted where appropriate. The Cochran’s Q test and the I 2 -heterogeneity test will be used to assess the presence of heterogeneity and whether the fixed or the random-effects model would be appropriate for combining study results using the inverse variance method or the DerSimonian-Lair method, respectively. Publication bias will be evaluated using funnel plots and Egger’s and Begg’s tests. The strength of the evidence will be assessed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Discussion: This systematic review will assess the effects of vitamin D supplementation on fasting glucose and triglyceride levels, waist circumference and mean blood pressure, and HDL-C among individuals with MetS. These findings may assist with decision-making within a clinical settingArtigo Inadequacies in the habitual nutrient intakes of patients with metabolic syndrome: a cross-sectional stud(Diabetology & Metabolic Syndrome, 2016-04) Evangelista, Karine Cavalcanti Maurício de Sena; Cunha, Aline Tuane Oliveira da; Pereira, Hermilla Torres; Aquino, Sephora Louyse Silva de; Sales, Cristiane Hermes; Lima, Josivan Gomes; Lima, Severina Carla Vieira Cunha; Pedrosa, Lucia Fatima CamposBackground: Dietary factors are important environmental factors associated with the prevalence of metabolic syn‑ drome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS. Methods: A cross-sectional study included 103 patients (82 % women) with MS seen at the endocrinology outpa‑ tient clinic of Hospital Universitario Onofre Lopes. Habitual nutrient intake data were collected at two 24-h dietary recalls. Macronutrient intake adequacies were classified according to the I Brazilian guidelines for the diagnosis and treatment of metabolic syndrome. The prevalence of inadequate micronutrient intake was estimated using the esti‑ mated average requirements (EAR) cut-point method after adjusting for intra- and interpersonal variances and energy. Results: The mean energy intake of the included patients was 1523.0 ± 592.2 kcal/d, higher in men (1884.0 vs. 1441.5 kcal/d in women; p = 0.003). The recommended percentage protein intake was exceeded in both women and men (18 % in women and 19 % in men). Although men consumed more fiber (18.8 vs. 13.3 g/d in women; p = 0.011), their intake was still inadequate. Women consumed more fat (47.6 vs. 41.3 g/d in men; p = 0.007). The prevalence of inadequate vitamin D and calcium intakes exceeded 80 % in both men and women and across all age groups. The same was observed for magnesium in men and women aged more than 30 years. The prevalence of inadequate vitamin E, riboflavin, and zinc intakes in men ranged from 50 to 75 %. The prevalence of inadequate vitamin A, vitamin C, thiamin, vitamin B6, copper, and selenium intakes in men and women was less than 50 %. Conclusions: Patients with MS had high protein intake, low fiber intake, and high a prevalence of inadequate vitamin D, magnesium, and calcium intakesArtigo Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study(Diabetology & Metabolic Syndrome, 2018-06) Fayh, Ana Paula Trussardi; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Pereira, Hermilla Torres; Freitas, Erika Paula Silva; Lima, Josivan Gomes; Lima, Severina Carla Vieira Cunha; Sena-Evangelista, Karine Cavalcanti Maurício; Pedrosa, Lucia Fátima CamposBackground: The risk of metabolic syndrome can be infuenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the infuence of environmental, biologi‑ cal, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome. Methods: This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years. The 25OHD concentration was considered the dependent variable; independent variables included age, sex, skin color, use of sunscreen, skin type, sun exposure score, ultraviolet radiation index, geographic location, season, body mass index, waist:hip ratio, waist circumference, parathyroid hormone level, total serum calcium level, and cal‑ cium and vitamin D intake. Results: The average vitamin D in individuals evaluated in summer 32±10 ng/mL was greater than in the winter 26±8 ng/mL (p<0.017). HDL-cholesterol was the only component of the MetS that difered signifcantly between the seasons (p<0.001), showing higher concentrations in autumn 45±8 mg/dL than in summer 35±8 mg/dL. In the multiple regression model, gender, WHR, sun exposure score, and winter vs. summer explained 10% of the variation in 25OHD concentration (p=0.004). Conclusions: Sex, waist:hip ratio, sun exposure, and summer season were predictors of 25OHD status among individuals with metabolic syndrome. HDL-cholesterol was the only component of metabolic syndrome that difered signifcantly between the seasons