Navegando por Autor "Pedrosa, Lucia Fátima Campos"
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Artigo Associations between components of metabolic Syndrome and demographic, nutritional, and lifestyle factors(Journal of Nutrition and Metabolism, 2024-01) Evangelista, Karine Cavalcanti Maurício de Sena; Lima, Layne Christina Benedito de Assis; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Peixoto, Talita do Nascimento; Lima, Severina Carla Vieira Cunha; Lima, Josivan Gomes; Pedrosa, Lucia Fátima CamposObjectives. To evaluate the associations between individuals with and without changes in components of metabolic syndrome (MetS) and demographic, nutritional, and lifestyle factors. Methods. A cross-sectional study was conducted with 224 individuals followed-up at a public hospital in Northeast Brazil. We used National Cholesterol Education Program-Adult Treatment Panel III (NCEP) criteria to diagnose MetS. We assessed components of MetS as dependent variables, while sex, age, food consumption, smoking, alcohol intake, physical activity, anthropometric parameters, and sleep hours were independent variables. Results. Comparing individuals with and without changes in components of MetS, the logistic regression models revealed that female sex was predictive of increased waist circumference and low HDL-c levels while advanced age was predictive of increased blood pressure and blood glucose levels. BMI emerged as a predictor for waist circumference and a protective factor for triglyceride levels. In addition, potassium intake, physical activity, and sleep duration were protective against decreased HDL-c, elevated triglyceride, and elevated blood pressure levels, respectively. Conclusion. Tis study demonstrated that sex, age, BMI, dietary potassium intake, physical activity, and hours of sleep are factors to be targeted in public health actions for prevention and treatment of MetSArtigo Associations between components of metabolic syndrome and demographic, nutritional, and lifestyle factors(Wiley, 2024) Lima, Severina Carla Vieira Cunha; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Peixoto, Talita do Nascimento; Lima, Layne Christina Benedito de Assis; Evangelista, Karine Cavalcanti Maurício Sena; Lima, Josivan Gomes; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0001-8268-1986Objectives. To evaluate the associations between individuals with and without changes in components of metabolic syndrome (MetS) and demographic, nutritional, and lifestyle factors. Methods. A cross-sectional study was conducted with 224 individuals followed-up at a public hospital in Northeast Brazil. We used National Cholesterol Education Program-Adult Treatment Panel III (NCEP) criteria to diagnose MetS. We assessed components of MetS as dependent variables, while sex, age, food consumption, smoking, alcohol intake, physical activity, anthropometric parameters, and sleep hours were independent variables. Results. Comparing individuals with and without changes in components of MetS, the logistic regression models revealed that female sex was predictive of increased waist circumference and low HDL-c levels while advanced age was predictive of increased blood pressure and blood glucose levels. BMI emerged as a predictor for waist circumference and a protective factor for triglyceride levels. In addition, potassium intake, physical activity, and sleep duration were protective against decreased HDL-c, elevated triglyceride, and elevated blood pressure levels, respectively. Conclusion. This study demonstrated that sex, age, BMI, dietary potassium intake, physical activity, and hours of sleep are factors to be targeted in public health actions for prevention and treatment of MetS.Artigo Astaxanthin: structural and functional aspects(Revista de Nutrição, 2024) Seabra, Larissa Mont’Alverne Jucá; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0002-1878-4283Astaxanthin, a carotenoid belonging to the xanthophyll class, has stirred great interest due to its antioxidant capacity and its possible role in reducing the risk of some diseases. Astaxanthin occurs naturally in microalgae, such as Haematococcus pluvialis and the yeast Phaffia rhodozyma, and has also been considered to be the major carotenoid in salmon and crustaceans. Shrimp processing waste, which is generally discarded, is also an important source of astaxanthin. The antioxidant activity of astaxanthin has been observed to modulate biological functions related to lipid peroxidation, having beneficial effects on chronic diseases such as cardiovascular disease, macular degeneration and cancer. Researches have shown that both astaxanthin obtained from natural sources and its synthetic counterpart produce satisfactory effects, but studies in humans are limited to natural sources. There is no established nutritional recommendation regarding astaxanthin daily intake but most studies reported beneficial results from a daily intake of 4mg. Thus, this review discusses some aspects of the carotenoid astaxanthin, highlighting its chemical structure and antioxidant activity, and some studies that report its use in humans.Artigo Carotenoides totais em resíduos do camarão litopenaeus vannamei(Revista Ceres, 2018) Seabra, Larissa Mont’Alverne Jucá; Damasceno, Karla Suzanne Florentino da Silva Chaves; Silva, Camila Ricioli da; Gomes, Camila de Carvalho; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0002-1878-4283Considerando-se o possível aproveitamento dos resíduos, provenientes do beneficiamento do camarão, realizou-se, neste trabalho, a determinação da concentração de carotenoides totais dos resíduos do camarão Litopenaeus vannamei e da farinha obtida após secagem. As análises foram realizadas nos resíduos in natura e na farinha recém-processada (dia 0) e aos 60, 120 e 180 dias de armazenamento sob congelamento. Os resíduos frescos apresentaram, no dia 0, teores de 42,74 μg/g de carotenoides totais e, a farinha recém-processada, de 98,51 μg/g. Após 180 dias de armazenamento, sob congelamento, os teores de carotenoides totais diminuíram significativamente, quando comparados com os do dia.Artigo Dietary intake of micronutrients and disease severity in patients with amyotrophic lateral sclerosis(Metabolites, 2023) Lais, Lucia Leite; Barros, Acsa Nara de Araújo Brito; Felipe, Maria Luisa do Nascimento; Barbosa, Isabelle Ribeiro; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0002-8061-7048Vitamins and essential metals have been studied as potential risk and prognostic factors in amyotrophic lateral sclerosis (ALS). This study aimed to evaluate the prevalence of inadequate micronutrient intake in ALS patients, comparing subgroups according to the disease severity. Data were obtained from the medical records of 69 individuals. Assessment of disease severity was determined by the revised ALS Functional Scale (ALSFRS-R), using the median as the cutoff. The prevalence of inadequate micronutrient intake was estimated using the Estimated Average Requirements (EAR) cut-point method. The prevalence of inadequate vitamin D, E, riboflavin, pyridoxine, folate, cobalamin, calcium, zinc, and magnesium intake was considered severe. Patients with lower ALSFRS-R scores had lower intakes of vitamin E (p < 0.001), niacin (p = 0.033), pantothenic acid (p = 0.037), pyridoxin (p = 0.008), folate (p = 0.009) and selenium (p = 0.001). Therefore, ALS patients should be monitored regarding dietary intake of micronutrients essential in neurological processes.Artigo Food frequency questionnaires developed and validated in Brazil: a scoping review protocol(Plos One, 2023) Lais, Lucia Leite; Barros, Acsa Nara de Araújo Brito; Felipe, Maria Luisa do Nascimento; Pedrosa, Lucia Fátima Campos; https://orcid.org/0000-0002-8061-7048A food frequency questionnaire (FFQ) is used to assess habitual food and nutrient intake. The choice of a FFQ should consider the study objectives, instrument particularities, target population, and geographic region. Over the past few years, FFQs have been constructed and validated in Brazil for children, adolescents, adults, athletes, and individuals with specific clinical conditions. The aim of this scoping review is to map the food frequency questionnaires developed and validated in Brazil. The Population-Concept-Context (PCC) framework was used for search strategy and defined as P—not applicable (open), C—food frequency questionnaire, and C—Brazil. FFQ validation studies performed with healthy or sick people will be included, regardless of clinical condition, age, sex, or region in the country. Studies with populations from other countries will be excluded. The review will be conducted in accordance with JBI (formerly known as Joanna Briggs Institute) methodology for scoping reviews. Search databases will include PubMed/MEDLINE, LILACS, Embase, Web of Science (ISI), Scopus, and Google Scholar. Data extraction will be performed by two independent reviewers and discrepancies resolved by a third reviewer. In order to improve the understanding and contextualization of the studies, a description of the results and presentation in tables and figures will be provided. Applications and implications for future research, practices, and policies will be discussed. Our protocol is registered through the Open Science Framework.Artigo Instruments for evaluation of motivations for weight loss in individuals with overweight and obesity: a systematic review and narrative synthesis(PLoS One, 2019-07) Lyra, Clélia de Oliveira; Silva, David Franciole Oliveira; Evangelista, Karine Cavalcanti Maurício Sena; Pedrosa, Lucia Fátima Campos; Arrais, Ricardo Fernando; Lima, Severina Carla Vieira CunhaThis systematic review aims to identify instruments used to assess motivations for weight loss in individuals with overweight and obesity from different age groups, such as children, adolescents, adults, and older adults. The virtual search was carried out using the PubMed, Scopus, LILACS, and ADOLEC databases, and by manual search. The following descriptors were used: questionnaire, scale, instrument, evaluation, motivation, motive, reason, “lose weight,” “losing weight,” “weight loss,” and slimming. Methodological quality was assessed according to the criteria of the COSMIN checklist. The search yielded 3,524 results, seven of which were included in the review. Six questionnaires assessing motivations for weight loss, which could be applied to various age groups, were identified. All the questionnaires presented items related to appearance and health as the main motivation for weight loss. In addition to these motivations, the questionnaires also included items related to improved sports performance, self-confidence, participation in important social events, family and social pressure, and fitting into different clothes. The most evaluated measurement properties in the studies were internal consistency, reliability, content validity, and construct validity. Regarding internal consistency, one was rated as excellent, one as fair, and three as poor. For reliability, two were rated as being of fair quality, and one as of poor quality. Two studies analyzed the content validity and the questionnaires were rated as being of poor methodological quality. Regarding structural validity, one was rated as excellent, another as fair, and another as poor quality. Only the Weight Loss Motivation Questionnaire presented excellent methodological quality for most of the analyzed criteria. There is a need to develop questionnaires that are of better methodological quality to assess motivations for weight loss. Instruments targeting the adolescent population should also be developedArtigo Instruments for evaluation of motivations for weight loss in individuals with overweight and obesity: a systematic review and narrative synthesis(Plos one, 2019) Lima, Severina Carla Vieira Cunha; Silva, David Franciole Oliveira; Evangelista, Karine Cavalcanti Maurício Sena; Lyra, Clélia Oliveira; Pedrosa, Lucia Fátima Campos; Arrais, Ricardo Fernando; https://orcid.org/0000-0001-8268-1986This systematic review aims to identify instruments used to assess motivations for weight loss in individuals with overweight and obesity from different age groups, such as children, adolescents, adults, and older adults. The virtual search was carried out using the PubMed, Scopus, LILACS, and ADOLEC databases, and by manual search. The following descriptors were used: questionnaire, scale, instrument, evaluation, motivation, motive, reason, “lose weight,” “losing weight,” “weight loss,” and slimming. Methodological quality was assessed according to the criteria of the COSMIN checklist. The search yielded 3,524 results, seven of which were included in the review. Six questionnaires assessing motivations for weight loss, which could be applied to various age groups, were identified. All the questionnaires presented items related to appearance and health as the main motivation for weight loss. In addition to these motivations, the questionnaires also included items related to improved sports performance, self-confidence, participation in important social events, family and social pressure, and fitting into different clothes. The most evaluated measurement properties in the studies were internal consistency, reliability, content validity, and construct validity. Regarding internal consistency, one was rated as excellent, one as fair, and three as poor. For reliability, two were rated as being of fair quality, and one as of poor quality. Two studies analyzed the content validity and the questionnaires were rated as being of poor methodological quality. Regarding structural validity, one was rated as excellent, another as fair, and another as poor quality. Only the Weight Loss Motivation Questionnaire presented excellent methodological quality for most of the analyzed criteria. There is a need to develop questionnaires that are of better methodological quality to assess motivations for weight loss. Instruments targeting the adolescent population should also be developed.Artigo Motivations for weight loss in adolescents with overweight and obesity: a systematic review(BMC Pediatrics, 2018) Lima, Severina Carla Vieira Cunha; Silva, David Franciole Oliveira; Evangelista, Karine Cavalcanti Maurício Sena; Lyra, Clélia Oliveira; Pedrosa, Lucia Fátima Campos; Arrais, Ricardo Fernando; https://orcid.org/0000-0001-8268-1986Background: Adolescents with overweight and obesity report various motivations for weight loss other than the desire for better health. However, there is little evidence regarding the main motivations for weight loss in adolescents. The present systematic review aimed to identify the motivations for weight loss in adolescents with overweight and obesity. Methods: A systematic search for original articles published up to December 2016 was carried out in the PubMed, Scopus, LILACS, and ADOLEC databases. The terms used in the search were: motivation, motive, reason, “weight loss,” “lose weight,” and adolescent. Results: Six studies (all cross-sectional) met the selection criteria and were included in the review. The instruments used to assess the participants’ motivations for weight loss were interviews and questionnaires with open questions. Seventeen motivations for weight loss were identified, the main ones being better health, esthetic/ cosmetic reasons, improvements in self-esteem, and avoidance of provocation/bullying. Conclusions: The results of the present review show the need for validated instruments to assess the motivations for weight loss in adolescents with overweight and obesity. Moreover, the high frequency of motivations for weight loss related to appearance and social acceptance evidences the need for multidisciplinary weight loss interventions that consider not only the biological factors, but also the psychological and social aspects.Artigo Motivations for weight loss in adolescents with overweight and obesity: a systematic review(BMC Pediatrics, 2018-11) Lyra, Clélia de Oliveira; Silva, David Franciole Oliveira; Evangelista, Karine Cavalcanti Maurício Sena; Pedrosa, Lucia Fátima Campos; Arrais, Ricardo Fernando; Lima, Severina Carla Vieira CunhaBackground: Adolescents with overweight and obesity report various motivations for weight loss other than the desire for better health. However, there is little evidence regarding the main motivations for weight loss in adolescents. The present systematic review aimed to identify the motivations for weight loss in adolescents with overweight and obesity. Methods: A systematic search for original articles published up to December 2016 was carried out in the PubMed, Scopus, LILACS, and ADOLEC databases. The terms used in the search were: motivation, motive, reason, “weight loss,” “lose weight,” and adolescent. Results: Six studies (all cross-sectional) met the selection criteria and were included in the review. The instruments used to assess the participants’ motivations for weight loss were interviews and questionnaires with open questions. Seventeen motivations for weight loss were identified, the main ones being better health, esthetic/ cosmetic reasons, improvements in self-esteem, and avoidance of provocation/bullying. Conclusions: The results of the present review show the need for validated instruments to assess the motivations for weight loss in adolescents with overweight and obesity. Moreover, the high frequency of motivations for weight loss related to appearance and social acceptance evidences the need for multidisciplinary weight loss interventions that consider not only the biological factors, but also the psychological and social aspectsArtigo Plasma levels of magnesium, calcium, calcium to magnesium ratio, and associations with metabolic syndrome and cardiometabolic risk factors(Biological Trace Element Research, 2024-02) Evangelista, Karine Cavalcanti Maurício de Sena; Moia, Melissa Nunes; Lima, Severina Carla Vieira Cunha; Nunes, Francisca Leide da Silva; Queiroz, Salomão Israel Monteiro Lourenço; Marchioni, Dirce Maria Lobo; Pedrosa, Lucia Fátima Campos; Barbosa, Fernando; Lyra, Clélia de OliveiraMagnesium and calcium are elements that have been associated with cardiometabolic risk factors related to metabolic syndrome (MetS). However, there are gaps in the knowledge regarding the impact of the calcium to magnesium (Ca/Mg) ratio in plasma. Thus, we aim to evaluate the associations between magnesium and calcium levels in plasma, and the Ca/Mg ratio in plasma with MetS components and other cardiometabolic risk factors. This cross-sectional study was carried out with 112 adults and older people, distributed into groups with (n = 60) and without MetS (n = 52). We evaluated sociodemographic, anthropometric, and biochemical data. Magnesium and calcium levels in plasma were measured by inductively coupled plasma mass spectrometry technique (ICP-MS). There was a high frequency of MetS, with no significant differences in magnesium and calcium levels and Ca/Mg ratio in plasma observed between groups. There were no associations between magnesium and MetS components or other cardiometabolic risk factors (all p > 0.05). Calcium levels were associated with total cholesterol (β = − 0.020; p = 0.000) and high-density lipoprotein cholesterol (HDL-c) (β = − 0.046; p = 0.005). The total cholesterol (β = − 0.025; p = 0.000) and low-density lipoprotein cholesterol (LDL-c) (β = 0.017; p = 0.020) were preditors of the Ca/Mg ratio. These results indicate important associations of calcium and the Ca/Mg ratio in plasma with cardiometabolic risk factors related to MetSArtigo Prediction equations for fat and fat-free body mass in adolescents, based on body circumferences(2012) Lyra, Clélia de Oliveira; Lima, Severina Carla Vieira Cunha; Lima, Kenio Costa de; Arrais, Ricardo Fernando; Pedrosa, Lucia Fátima CamposFat mass (FM) and fat-free body mass (FFB) are important parameters for assessing nutritional status, since they are associated with higher prevalence of excess body fat and malnutrition worldwide. To develop prediction equations for fat and fat-free body mass in adolescents using body circumferences. This cross-sectional study included 218 adolescents (10-16 years) with normal weight as defined by body mass index. FM(Pred) and FFB(Pred) were estimated using stepwise multiple linear regression, considering age and body circumferences. Response variables, FM(BIA) and FFB(BIA) were estimated using bioelectric impedance analysis (BIA). The accuracy of the prediction equations was evaluated using the coefficient of determination (R(2)) and Akaike's Information Criterion (AIC). The best prediction equations for males were FM(Pred) = -7.114 - 0.592(age) - 0.958(wrist)+0.191(hip)+0.295(abdomen); R(2) = 0.552; AIC = 416.04 and FFB(Pred) = - 52.180+1.913(age)+1.954(wrist)+1.635(forearm); R(2) = 0.869; AIC = 578.24. For females, the best equations were FM(Pred) = -17.580 - 0.678(wrist)+0.221(abdomen)+0.241(hip)+0.202(proximal thigh) - 0.228(calf); R(2) = 0.838; AIC = 415.36 and FFB(Pred) = -31.066+0.90(age)+1.090(wrist) - 0.139(abdomen)+0.326(hip)+0.632(calf); R(2) = 0.878; AIC = 512.48. The equations developed to estimate fat body mass in females and fat-free body mass in both genders had high adjusted coefficients of determination and are therefore preferable to those derived using BIA.Artigo Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study(Diabetology & Metabolic Syndrome, 2018-06) Fayh, Ana Paula Trussardi; Aquino, Séphora Louyse Silva; Cunha, Aline Tuane Oliveira da; Pereira, Hermilla Torres; Freitas, Erika Paula Silva; Lima, Josivan Gomes; Lima, Severina Carla Vieira Cunha; Sena-Evangelista, Karine Cavalcanti Maurício; Pedrosa, Lucia Fátima CamposBackground: The risk of metabolic syndrome can be infuenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the infuence of environmental, biologi‑ cal, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome. Methods: This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years. The 25OHD concentration was considered the dependent variable; independent variables included age, sex, skin color, use of sunscreen, skin type, sun exposure score, ultraviolet radiation index, geographic location, season, body mass index, waist:hip ratio, waist circumference, parathyroid hormone level, total serum calcium level, and cal‑ cium and vitamin D intake. Results: The average vitamin D in individuals evaluated in summer 32±10 ng/mL was greater than in the winter 26±8 ng/mL (p<0.017). HDL-cholesterol was the only component of the MetS that difered signifcantly between the seasons (p<0.001), showing higher concentrations in autumn 45±8 mg/dL than in summer 35±8 mg/dL. In the multiple regression model, gender, WHR, sun exposure score, and winter vs. summer explained 10% of the variation in 25OHD concentration (p=0.004). Conclusions: Sex, waist:hip ratio, sun exposure, and summer season were predictors of 25OHD status among individuals with metabolic syndrome. HDL-cholesterol was the only component of metabolic syndrome that difered signifcantly between the seasonsArtigo Processed and ultra-processed foods are associated with high prevalence of inadequate selenium intake and low prevalence of vitamin B1 and zinc inadequacy in adolescents from public schools in an urban area of northeastern Brazil(PLoS One, 2019-12) Lyra, Clélia de Oliveira; Falcão, Raphaela Cecília Thé Maia de Arruda; Morais, Célia Márcia Medeiros de; Pinheiro, Liana Galvão Bacurau; Pedrosa, Lucia Fátima Campos; Lima, Severina Carla Vieira Cunha; Evangelista, Karine Cavalcanti Maurício SenaChanges in eating behavior of adolescents are associated with high consumption of processed and ultra-processed foods. This study evaluated the association between these foods and the prevalence of inadequate micronutrient intake in adolescents. A cross-sectional study was conducted with 444 adolescents from public schools in the city of Natal, northeastern Brazil. The adolescents’ habitual food consumption was evaluated using two 24-hour dietary recalls. Foods were categorized according to the degree of processing (processed and ultra-processed) and distributed into energy quartiles, using the NOVA classification system. Inadequacies in micronutrient intake were assessed using the estimated average requirement (EAR) as the cutoff point. Multivariate logistic regression models were used to estimate the relationship between energy percentage from processed and ultra-processed foods and prevalence of inadequate micronutrient intake. The mean (Standard Deviation (SD)) consumption of total energy from processed foods ranged from 5.8% (1.7%) in Q1 to 20.6% (2.9%) in Q4, while the mean consumption of total energy from ultra-processed foods ranged from 21.4% (4.9%) in Q1 to 61.5% (11.7%) in Q4. The rates of inadequate intake of vitamin D, vitamin E, folate, calcium, and selenium were above 80% for both sexes across all age groups. Energy consumption from processed foods was associated with higher prevalence of inadequate selenium intake (p < 0.01) and lower prevalence of inadequate vitamin B1 intake (p = 0.04). Energy consumption from ultra-processed foods was associated with lower prevalence of inadequate zinc and vitamin B1 intake (p < 0.01 and p = 0.03, respectively). An increase in the proportion of energy obtained from processed and ultra-processed foods may reflect higher prevalence of inadequate selenium intake and lower prevalence of vitamin B1 and zinc inadequacyTCC Variação sazonal dos componentes da síndrome metabólica em indivíduos adultos e idosos(Universidade Federal do Rio Grande do Norte, 2017) Cruz, Bruno Diego de Sousa; Pedrosa, Lucia Fátima Campos; Séphora Louyse Silva de AquinoObjetivo: avaliar em indivíduos com síndrome metabólica a frequência dos componentes da síndrome metabólica de acordo com as estações do ano. Metodologia: Estudo transversal, realizado com 180 indivíduos (18-80 anos) diagnosticados com síndrome metabólica e distribuídos nas estações do ano, de acordo com a data de realização dos exames bioquímicos. Foram realizadas as medidas antropométricas, de pressão arterial, análise do perfil lipídico e glicemia de jejum. O consumo alimentar foi avaliado utilizando-se o recordatório 24 horas e as informações de hábitos de vida foram obtidas por meio de questionário. Resultados: a média de idade foi de 50,11(12,26) anos, com predomínio do sexo feminino (78%). A média do IMC foi de 33,38(6,82) kg/m2; 106 (59%) não eram tabagistas, 145 (81%) não consumiam bebida alcoólica e 107 (59%) praticavam atividade física. A concentração de HDL colesterol diferiu significativamente entre as estações do ano (p=0,014), observando-se uma menor concentração desse componente no verão de 32,54(6,89) mg/dL. A frequência dos outros componentes da síndrome metabólica não diferiu significativamente entre as estações. Conclusões: HDL colesterol apresentou variação sazonal com maior comprometimento metabólico no verão, mostrando a importância de avaliar a sazonalidade dos componentes da síndrome metabólica no atendimento clínico.