Navegando por Autor "Piuvezam, Márcia Regina"
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Artigo The control and prevention of COVID-19 transmission in children: a protocol for systematic review and meta-analysis(Lippincott, Williams & Wilkins, 2020-07-31) Medeiros, Gidyenne Christine Bandeira Silva de; Nunes, Ana Clara de França; Azevedo, Kesley Pablo Morais de; Oliveira Segundo, Victor Hugo de; Santos, Gilberto Martins; Mata, Ádala Nayana de Sousa; Pimenta, Isac Davidson; Bezerra, Isaac Newton Machado; Braga, Liliane Pereira; Capucho, Helaine Carneiro; Piuvezam, Márcia Regina; Barbosa Filho, Valter Cordeiro; Leitão, José Carlos; Martínez, Daniel Guillén; Piuvezam, GrasielaBackground: The pandemic following the rapid spread of the new SARS-CoV-2 virus has hit all continents and caused thousands of deaths worldwide. Evidence has been published on epidemiological and clinical characteristics of population groups considered at risk; however, information for the other population groups, especially for the child population, is needed. In this context, this protocol describes a systematic review that will aim to identify the evidence on control and prevention of COVID-19 transmission among children and adolescents, as well as to describe the epidemiological profile and clinical and immunological characteristics of COVID-19 in this population. Methods: This protocol will be developed in accordance with PRISMA-P. The searches will be conducted in PubMed, Web of Science, ScienceDirect, EMBASE, and Scopus, seeking clinical trials. Observational studies and case reports with Children and adolescents ( 19 years) infected with SARS-CoV-2 will be included whether they report information on the control of prevention and COVID-19 transmission. Two independent researchers will perform the selection of articles, removal of duplication, and screening by Rayyan QCRI application. Cochrane’s RoB 2.0, ROBINS-I, and CASP tools will be used to assess the risk of bias. Meta-analysis, subgroup analyses, and/or descriptive analyses will be carried out based on the data conditions included. Results: A high-quality synthesis of the available evidences on the epidemiological profile, the clinical and immunological characteristics involved in children, and adolescents diagnosed with COVID-19, as well as the participation of this population in the transmission dynamics of SARS-CoV-2 will be provided. Conclusion: This systematic review has an important relevance in the current context because it has a great potential to help the development of new control and prevention strategies in the pediatric population. Record of systematic review: CRD42020179263. Abbreviations: CASP = Critical Appraisal Skills Program, COVID-19 = Corona Virus Disease (2019), PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-Analyses, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, RoB = Risk of bias, ROBINS-I = Risk of Bias in Non-Randomised Studies – of Interventions, SARS-CoV-2 = Severe Acute Respiratory Syndrome Coronavirus 2