Instituto do Cérebro
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Article Amyloid-beta peptides trigger premature functional and gene expression alterations in human-induced neurons(Biomedicines, 2023) Farias, Ana Raquel Melo de; Pelletier, Alexandre; Carvalho, Lukas Iohan da Cruz; Saha, Orthis; Bonnefond, Amélie; Amouyel, Philippe; Delahaye, Fabien; Lambert, Jean-Charles; Costa, Marcos Romualdo; https://orcid.org/0000-0003-4324-6759Article The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons(Springer Science and Business Media LLC, 2024-03) Saha, Orthis; Farias, Ana Raquel Melo de; Pelletier, Alexandre; Siedlecki-Wullich, Dolores; Landeira, Bruna Soares; Gadaut, Johanna; Carrier, Arnaud; Vreulx, Anaïs-Camille; Guyot, Karine; Shen, Yun; Bonnefond, Amelie; Amouyel, Philippe; Tcw, Julia; Kilinc, Devrim; Queiroz, Claudio Marcos Teixeira de; Delahaye, Fabien; Lambert, Jean-Charles; Costa, Marcos RomualdoArticle The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects(2022-01-08) Lambert, Erwan; Saha, Orthis; Landeira, Bruna Soares; Farias, Ana Raquel Melo de; Hermant, Xavier; Carrier, Arnaud; Pelletier, Alexandre; Gadaut, Johanna; Davoine, Lindsay; Dupont, Cloé; Amouyel, Philippe; Bonnefond, Amélie; Lafont, Frank; Abdelfettah, Farida; Verstreken, Patrik; Chapuis, Julien; Barois, Nicolas; Delahaye, Fabien; Dermaut, Bart; Lambert, Jean‑Charles; Costa, Marcos Romualdo; Dourlen, PierreArticle Differential transcript usage unravels gene expression alterations in Alzheimer’s disease human brains(Springer Science and Business Media LLC, 2021-01-04) Coelho, Diego Marques; Iohan, Lukas da Cruz Carvalho; Farias, Ana Raquel Melo de; Flaig, Amandine; Lambert, Jean-Charles; Costa, Marcos Romualdo