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Title: Human papillomavirus infection in women attendes at a cervical cancer screening service in Natal, Brazil
Authors: Fernandes, Thales Allyrio Araújo de Medeiros
Meissner, Rosely de Vasconcellos
Bezerra, Laelson Freire
Azevedo, Paulo Roberto Medeiros de
Fernandes, José Veríssimo
Keywords: Human papillomavirus;Cervical cancer;Epidemiology;Prevalence;Risk factors
Issue Date: Jul-2008
Publisher: Brazilian Journal of Microbiology
Citation: FERNANDES, T. A. A. M.; et al. Human papillomavirus infection in women attended at a cervical cancer screening service in Natal, Brazil. Brazilian Journal of Microbiology, v. 39, p. 238-240, 2008. Disponível em: Acesso em: 08 dez. 2017
Portuguese Abstract: We analyzed cervical specimens of 202 women, aged 15 to 64 years, attended at Luis Antonio Hospital, Natal, Brazil, to determine the prevalence of HPV and identify the more frequent genotypes and risk factors for HPV nfection in women attended at a cervical cancer screening service. Two specimens were collected from each patient: one for cytological examination and the other to detect HPV DNA by PCR, and typing by dot blot hybridization. A total of 54.5% of the sample had normal cytology and 45.5% had cytological alterations. HPV was detected in 24.5% of the cytologically normal women and in 59.8% of those with altered cytology. Both single and double HPV infection increased the likelihood of cytological alterations. Thirteen types of HPV were identified, most of which were high risk. HPV 16 was the most prevalent single-type infection, followed by HPV 58. The most frequent double infection was the association between HPV 56 and 57. The prevalence of HPV in cytologically normal women was greater than that reported for countries on all the continents except Africa. The inverse was observed in women with cytological alterations. The distribution of HPV types was similar to that described for the Americas, with some differences. Multiple sexual partners was the only risk factor showing an association with the presence of HPV infection.
ISSN: 1517-8382
Appears in Collections:CCET - DEST - Artigos publicados em periódicos

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