Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America

Ribeiro-dos-Santos, André M.; Vidal, Amanda Ferreira; Vinasco-Sandoval, Tatiana; Guerreiro, João; Santos, Sidney; Ribeiro-dos-Santos, Ândrea; Souza, Sandro José de

Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America

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dc.contributor.author	Ribeiro-dos-Santos, André M.
dc.contributor.author	Vidal, Amanda Ferreira
dc.contributor.author	Vinasco-Sandoval, Tatiana
dc.contributor.author	Guerreiro, João
dc.contributor.author	Santos, Sidney
dc.contributor.author	Ribeiro-dos-Santos, Ândrea
dc.contributor.author	Souza, Sandro José de
dc.date.accessioned	2020-10-29T18:26:58Z
dc.date.available	2020-10-29T18:26:58Z
dc.date.issued	2020-10-29
dc.description.resumo	Studies on the peopling of South America have been limited by the paucity of sequence data from Native Americans, especially from the east part of the Amazon region. Here, we investigate the whole exome variation from 58 Native American individuals (eight different populations) from the Amazon region and draw insights into the peopling of South America. By using the sequence data generated here together with data from the public domain, we confirmed a strong genetic distinction between Andean and Amazonian populations. By testing distinct demographic models, our analysis supports a scenario of South America occupation that involves migrations along the Pacific and Atlantic coasts. Occupation of the southeast part of South America would involve migrations from the north, rather than from the west of the continent	pt_BR
dc.identifier.citation	RIBEIRO-DOS-SANTOS, André M.; VIDAL, Amanda Ferreira; VINASCO-SANDOVAL, Tatiana; GUERREIRO, João; SANTOS, Sidney; RIBEIRO-DOS-SANTOS, Ândrea; SOUZA, Sandro José de. Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America. Frontiers In Genetics, [S. l.], v. 11, p. 548505, out. 2020. http://dx.doi.org/10.3389/fgene.2020.548507. Disponível em: https://www.frontiersin.org/articles/10.3389/fgene.2020.548507/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE. Acesso em: 29 out. 2020.	pt_BR
dc.identifier.doi	https://doi.org/10.3389/fgene.2020.548507
dc.identifier.uri	https://repositorio.ufrn.br/handle/123456789/30514
dc.language	en	pt_BR
dc.publisher	Frontiers Media SA	pt_BR
dc.rights	Attribution 3.0 Brazil	*
dc.rights.uri	http://creativecommons.org/licenses/by/3.0/br/	*
dc.subject	Amazon	pt_BR
dc.subject	Native populations	pt_BR
dc.subject	Exome	pt_BR
dc.subject	Genomics	pt_BR
dc.subject	SNP (Single Nucleotide Polymorphism)	pt_BR
dc.title	Exome sequencing of native populations from the Amazon reveals patterns on the peopling of South America	pt_BR
dc.type	article	pt_BR