Factors associated with increased alpha-tocopherol content in milk in response to maternal supplementation with 800 IU of vitamin E
| dc.contributor.author | Ribeiro, Karla Danielly da Silva | |
| dc.contributor.author | Rebouças, Amanda de Sousa | |
| dc.contributor.author | Silva, Ana Gabriella Costa Lemos da | |
| dc.contributor.author | Oliveira, Amanda Freitas de | |
| dc.contributor.author | Silva, Lorena Thalia Pereira da | |
| dc.contributor.author | Felgueiras, Vanessa de Freitas | |
| dc.contributor.author | Cruz, Marina Sampaio | |
| dc.contributor.author | Silbiger, Vivian Nogueira | |
| dc.contributor.author | Dimenstein, Roberto | |
| dc.contributor.authorID | 0000-0002-2251-5967 | pt_BR |
| dc.date.accessioned | 2024-11-26T20:57:04Z | |
| dc.date.available | 2024-11-26T20:57:04Z | |
| dc.date.issued | 2019 | |
| dc.description.resumo | Background: Vitamin E supplementation might represent an efficient strategy to increase the vitamin E content in milk. The present study aimed to evaluate the impact of supplementation with 800 IU RRR-alpha-tocopherol on the alpha-tocopherol content of milk and the factors associated with the increase in vitamin E. Methods: Randomized clinical trial with 79 lactating women from Brazil, who were assigned to the control group, or to the supplemented group (800 IU of RRR-alpha-tocopherol). Milk and serum were collected between 30 and 90 days after delivery (collection 1), and on the next day (collection 2). Alpha-tocopherol was analyzed using high-performance liquid chromatography. Results: In the supplemented group, the alpha-tocopherol content in serum and milk increased after supplementation (p < 0.001). In the multivariate analysis, only alpha-tocopherol in milk (collection 1) was associated with the level of this vitamin in milk after supplementation (β = 0.927, p < 0.001), and binary logistic regression showed that the dietary intake was the only determinant for the greater effect of supplementation in milk. Conclusion: The pre-existing vitamin level in milk and diet are determinants for the efficacy of supplementation in milk, suggesting that in populations with vitamin E deficiency, high-dose supplementation can be used to restore its level in milk. | pt_BR |
| dc.identifier.citation | REBOUÇAS, Amanda de Sousa; SILVA, Ana Gabriella Costa Lemos da; OLIVEIRA, Amanda Freitas de; SILVA, Lorena Thalia Pereira da; FELGUEIRAS, Vanessa de Freitas; CRUZ, Marina Sampaio; SILBIGER, Vivian Nogueira; RIBEIRO, Karla Danielly da Silva; DIMENSTEIN, Roberto. Factors associated with increased alpha-tocopherol content in milk in response to maternal supplementation with 800 IU of vitamin E. Nutrients, v. 11, p. 1 - 14, 2019. DOI:http://dx.doi.org/10.3390/nu11040900. Disponível em: https://www.mdpi.com/2072-6643/11/4/900. Acesso em: 07 out. 2024. | pt_BR |
| dc.identifier.issn | 2072-6643 | |
| dc.identifier.uri | https://repositorio.ufrn.br/handle/123456789/60684 | |
| dc.language | en | pt_BR |
| dc.publisher | Nutrients | pt_BR |
| dc.rights | Attribution 3.0 Brazil | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/br/ | * |
| dc.subject | Clinical trial | pt_BR |
| dc.subject | Lactation | pt_BR |
| dc.subject | Infants | pt_BR |
| dc.subject | Breastfeeding | pt_BR |
| dc.subject | Lactating women | pt_BR |
| dc.title | Factors associated with increased alpha-tocopherol content in milk in response to maternal supplementation with 800 IU of vitamin E | pt_BR |
| dc.type | article | pt_BR |
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