Estudo das variações dos níveis de retinol no colostro humano de parturientes a termo e pré-termo

Abstract

Objectives: to analyze retinol levels variations in the colostrum of term and pre-term parturient women. Methods: colostrum samples of 78 lactating women, half of which were mothers of premature new borns, were analyzed. The samples were manually extracted from one breast until 2.0 ml were obtained. They were collected up to 72 hours after birth, during the morning hours and right before nursing. Retinol levels were determined by high-performance liquid chromatography and analyzed by the T-test for means comparison. Results: the mean retinol values in the colostrums of women with term (n = 39) and pre-term newborns (n = 39) were 89,4 ± 46,1 μg/dL and 55,6 ± 27,7 μg/dL, respectively. The difference of means was considered statistically significant at (p < 0,001). Human milk meets the need for Vitamin A in the term newborn. However, for the premature newborn, it only supplied 66% of the needs. Conclusions: results suggest that exclusive use of human milk does not meet the needs of pre-term newborn completely and that a Vitamin A supplement for the mother is necessary in order to reduce Vitamin A risk deficiency.