Association between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adults

Página do item simplificado Estatísticas
dc.contributor.authorEvangelista, Karine Cavalcanti Maurício de Sena
dc.contributor.authorPacheco, Daniela Antunes
dc.contributor.authorCampêlo, Angélica Lopes de Sousa
dc.contributor.authorSousa, Sara Estéfani Soares de
dc.contributor.authorSales, Márcia Cristina
dc.contributor.authorBarbosa Júnior, Fernando
dc.contributor.authorLima, Kenio Costa
dc.contributor.authorFerreira, Marcelo Rodrigo Portela
dc.contributor.authorReis, Bruna Zavarize
dc.contributor.authorPedrosa, Lucia Fatima Campos
dc.date.accessioned2024-08-23T19:53:40Z
dc.date.available2024-08-23T19:53:40Z
dc.date.issued2024-09
dc.description.resumoBackground: Older adults have a progressive deficiency in the ability to detoxify chemical elements and are susceptible to dyslipidemia and changes in glycemic control. The objective was to evaluate the association of the mixture of essential and toxic elements in the plasma of institutionalized older adults and test the associations with lipid profile variables and glycemic control. Methods: Data were obtained from 149 Brazilian older adults aged ≥60 living in nursing homes (NH) in Natal, Brazil. The concentrations of sixteen chemical elements in plasma and lipid profile parameters and glycemic control of 149 institutionalized older adults were measured. Bayesian kernel machine regression was used to estimate the associations of the mixture of chemical elements with total cholesterol (TC), high-density lipoprotein (HDL-c), low-density lipoprotein (LDL-c), triglycerides (TG), fasting glucose, and glycated hemoglobin. ResultsNon-linear responses to exposure were observed for iron (Fe) about TC, LDL-c, and TG, and for barium (Ba) and copper (Cu) about TG. The concentration of the mixture of chemical elements below the 35th percentile was associated with a decrease in TC. Fe was the main element in the effect of the mixture associated with TC.ConclusionsThe lower concentrations of the mixture of chemical elements in plasma had a protective effect on the increase in TC, with Fe being the main element. Considering the results, the levels of essential and toxic elements in the plasma of older adults require extensive screening, mainly to prevent dyslipidemia and monitor clinical interventionspt_BR
dc.identifier.citationPACHECO, Daniela Antunes; CAMPÊLO, Angélica Lopes de Sousa; SOUSA, Sara Estéfani Soares de; SALES, Márcia Cristina; EVANGELISTA, Karine Cavalcanti Maurício de Sena; BARBOSA JÚNIOR, Fernando; LIMA, Kenio Costa; FERREIRA, Marcelo Rodrigo Portela; REIS, Bruna Zavarize; PEDROSA, Lucia Fatima Campos. Association between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adults. Journal of Trace Elements in Medicine and Biology, [S.l.], v. 85, p. 1-9, set. 2024. DOI: 10.1016/j.jtemb.2024.127490. Disponível em: https://www.sciencedirect.com/science/article/pii/S0946672X2400110X?via%3Dihub. Acesso em: 25 jul. 2024.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1016/j.jtemb.2024.127490
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/59852
dc.languageenpt_BR
dc.publisherJournal of Trace Elements in Medicine and Biologypt_BR
dc.subjectToxic elementspt_BR
dc.subjectEssential elementspt_BR
dc.subjectOlder adultspt_BR
dc.subjectNursing homespt_BR
dc.subjectLipid profilept_BR
dc.titleAssociation between exposure to plasma mixture of essential and toxic elements and the lipid profile in institutionalized older adultspt_BR
dc.typearticlept_BR

Arquivos

Licença do Pacote

Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.45 KB
Formato:
Item-specific license agreed upon to submission
Nenhuma Miniatura disponível
Baixar

Coleções

CCS - DNUT - Artigos publicados em periódicos
Repositório Institucional - UFRN Campus Universitário Lagoa NovaCEP 59078-970 Caixa postal 1524 Natal/RN - BrasilUniversidade Federal do Rio Grande do Norte© Copyright 2025. Todos os direitos reservados.
Contato+55 (84) 3342-2260 - R232Setor de Repositórios Digitaisrepositorio@bczm.ufrn.br
DSpaceIBICT
OasisBR
LAReferencia
Customizado pela CAT - BCZM