Clinical characteristics of Guillain–Barré syndrome in a tropical country: a Brazilian experience

dc.contributor.authorDourado Junior, Mário Emílio Teixeira
dc.contributor.authorFélix, R. H.
dc.contributor.authorSilva, W. K. A. da
dc.contributor.authorQueiroz, J. W.
dc.contributor.authorJeronimo, Selma Maria Bezerra
dc.contributor.authorIDhttps://orcid.org/0000-0002-9462-2294pt_BR
dc.date.accessioned2023-07-28T14:20:21Z
dc.date.available2023-07-28T14:20:21Z
dc.date.issued2011
dc.description.resumoObjective – To analyze the clinical variants, outcomes, and prognosis of Guillain–Barré syndrome (GBS) in a Brazilian population. Materials and methods – Clinical and laboratory data of 149 cases of GBS diagnosed from 1994 to 2007 were analyzed. Results – Acute inflammatory demyelinating polyneuropathy (AIDP) was the most frequent variant (81.8%) of GBS, followed by acute motor axonal neuropathy (AMAN) (14.7%) and acute motor and sensory axonal neuropathy (AMSAN) (3.3%). The incidence of GBS was 0.3/100,000 for the state of Rio Grande do Norte and cases occurred at a younger age. GBS was preceded by infections, with the axonal variant associated with episodes of diarrheas (P = 0.025). Proximal weakness was more frequent in AIDP, and distal weakness predominant in the axonal variant. Compared to 42.4% of cases with AIDP (P < 0.0001), 84.6% of cases with the axonal variant had nadir in <10 days. Individuals with the axonal variant took longer to recover deambulation (P < 0.0001). The mortality of GBS was 5.3%. Conclusion – A predominance of the AIDP variant was seen, and the incidence of the disease decreased with age. As expected, the distribution of weakness correlated with the clinical variants, and individuals with the axonal variant had a poorer prognosis.pt_BR
dc.identifier.citationDOURADO JUNIOR, Mário Emílio Teixeira; FÉLIX, R. H.; SILVA, W. K. A. da; QUEIROZ, J. W.; JERONIMO, S. M. B.. Clinical characteristics of Guillain-Barré syndrome in a tropical country: a brazilian experience. Acta Neurologica Scandinavica, [S.L.], v. 125, n. 1, p. 47-53, 24 mar. 2011. Hindawi Limited. http://dx.doi.org/10.1111/j.1600-0404.2011.01503.x. Disponível em: https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0404.2011.01503.x. Acesso em: 24 jul. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1111/j.1600-0404.2011.01503.x
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/54259
dc.languageenpt_BR
dc.publisherActa Neurologica Scandinavicapt_BR
dc.subjectguillain-barré syndromept_BR
dc.subjectelectromyographypt_BR
dc.subjectcritical carept_BR
dc.subjectneuroimmunologypt_BR
dc.subjectneuropathypt_BR
dc.subjectperipheral neuropathypt_BR
dc.titleClinical characteristics of Guillain–Barré syndrome in a tropical country: a Brazilian experiencept_BR
dc.typearticlept_BR

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