α-Tocopherol in breast milk of women with preterm delivery after a single postpartum oral dose of vitamin E
dc.contributor.author | Neves, Renata Alexandra Moreira das | |
dc.contributor.author | Medeiros, Jeane Franco Pires | |
dc.contributor.author | Ribeiro, Karla Danielly da Silva | |
dc.contributor.author | Lima, Mayara Santa Rosa | |
dc.contributor.author | Lima, Amanda Cibely Pinheiro | |
dc.contributor.author | Dantas, Raquel Costa Silva | |
dc.contributor.author | Silva, Alyne Batista da | |
dc.contributor.author | Dimenstein, Roberto | |
dc.contributor.authorID | https://orcid.org/0000-0003-1014-0536 | |
dc.contributor.authorID | https://orcid.org/0000-0002-2251-5967 | |
dc.contributor.authorID | https://orcid.org/0000-0003-3006-7700 | |
dc.contributor.authorID | https://orcid.org/0000-0001-8517-6811 | |
dc.date.accessioned | 2025-05-26T19:54:41Z | |
dc.date.available | 2025-05-26T19:54:41Z | |
dc.date.issued | 2016-03-02 | |
dc.description.resumo | We evaluated the effect of maternal vitamin E supplementation on the α-tocopherol concentrations of colostrum, transitional milk and mature milk of women who had given birth prematurely. This longitudinal randomised-controlled trial divided eighty-nine women into two groups: a control group and a supplemented group. Blood and breast milk were collected from all the participants after delivery. Next, each woman in the supplemented group received 400 IU of RRR-α-tocopheryl acetate. Further breast milk samples were collected 24 h after the first collection, as well as 7 and 30 d after delivery. α-Tocopherol concentrations were determined by HPLC. The baseline α-tocopherol concentrations in the maternal serum of the two groups were similar: 1159·8 (SD 292·4) μg/dl (27·0 (SD 6·8) μmol/l) for the control group and 1128·3 (SD 407·2) μg/dl (26·2 (SD 9·5) μmol/l) for the supplemented group. None of the women was vitamin E deficient. Breast milk α-tocopherol concentrations increased by 60 % 24 h after supplementation in the intervention group and did not increase at all in the control group. α Tocopherol concentration of the transitional milk in the supplemented group was 35 % higher compared with the control group. α-Tocopherol concentrations of the mature milk in both groups were similar. Maternal supplementation with 400 IU of RRR-α-tocopherol increased the vitamin E concentrations of the colostrum and transitional milk, but not of the mature milk. This study presents relevant information for the design of strategies to prevent and combat vitamin E deficiency in the risk group of preterm infants | |
dc.identifier.citation | MEDEIROS, Jeane Franco Pires; RIBEIRO, Karla Danielly da Silva; LIMA, Mayara Santa Rosa; NEVES, Renata Alexandra Moreira das; LIMA, Amanda Cibely Pinheiro; DANTAS, Raquel Costa Silva; SILVA, Alyne Batista da; DIMENSTEIN, Roberto. α-Tocopherol in breast milk of women with preterm delivery after a single postpartum oral dose of vitamin E. British Journal of Nutrition, [S.l.], v. 115, n. 8, p. 1424-1430, 2 mar. 2016. DOI: 10.1017/s0007114516000477. Disponível em: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/tocopherol-in-breast-milk-of-women-with-preterm-delivery-after-a-single-postpartum-oral-dose-of-vitamin-e/8759423FFED1EC4836659BECFE7C7F74. Acesso em: 8 jul. 2024. | |
dc.identifier.uri | https://doi.org/10.1017/S0007114516000477 | |
dc.identifier.uri | https://repositorio.ufrn.br/handle/123456789/63648 | |
dc.language.iso | en_US | |
dc.publisher | British Journal of Nutrition | |
dc.subject | Dietary supplementation | |
dc.subject | Clinical trials | |
dc.subject | Intervention studies | |
dc.subject | Liquid chromatography | |
dc.title | α-Tocopherol in breast milk of women with preterm delivery after a single postpartum oral dose of vitamin E | |
dc.type | article |
Arquivos
Pacote Original
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- a-TocopherolBreast_Medeiros_2016.pdf
- Tamanho:
- 677.83 KB
- Formato:
- Adobe Portable Document Format
Nenhuma Miniatura disponível
Licença do Pacote
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- license.txt
- Tamanho:
- 1.53 KB
- Formato:
- Item-specific license agreed upon to submission
Nenhuma Miniatura disponível