Efeitos imediatos da VNI na função muscular periférica e desempenho aeróbico em pacientes com doença pulmonar obstrutiva crônica

Abstract

Objective: To evaluate the acute effect of BINV on peripheral muscle function without isokinetic exercise and non-TC6 aerobic performance in COPD. Methods: Nonprobabilistic sample, totaling 14 individuals with moderate to very severe COPD, without exacerbations. Procedures carried out in two days. Initially all criteria preceded clinical evaluation, disease severity, questionnaires to explain and quality of life, spirometry and manovacuometry. Secondarily taken for collection biochemistry, 6MWT, and isokinetic evaluation of the quadriceps, all basal. Then they underwent the intervention with 30 minutes of NIV Binible / placebo, according to randomization; submitted to new TC6 and test protocol in the isokinetic dynamometer, ending with a new biochemical collection. Before and after the assessment was quantified to a relative perception of dyspnea and fatigue in After washing the nobility days, participants returned, re-developing all procedures, and altering NIV according to randomization. Results: 14 participants, 57% with severe COPD and moderate COPD, a NIV showed significant improvement in the performance of lower and lower actions, isokinetic post-exercise (p≤0.02 * and ≤0.05 *), improvement in values peak torque (p≤0.00 *), total work (p≤0.00 *), fatigue index (p≤0.00 *) and power (p≤0.01 *), the NIV group walked approximately 16 meters more than the 6MWT, and obtained better in blood lactate levels (p≤0.00 *). Conclusion: A NIV directly improves the perception of dyspnea and scores assessed in isokinetic exercise. It presents clinical results on non-TC6 sub-percolation, and improvement of the blood lactate level, in patients with COPD.