Clinical presentation, outcomes, and treatment of membranous nephropathy after transplantation

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dc.contributor.authorSilva, Artur Quintiliano Bezerra da
dc.contributor.authorSandes-Freitas, Taina V. de
dc.contributor.authorMansur, Juliana B.
dc.contributor.authorMedicina-Pestana, Jose Osmar
dc.contributor.authorMastroianni-Kirsztajn, Gianna
dc.date.accessioned2023-05-19T16:44:26Z
dc.date.available2023-05-19T16:44:26Z
dc.date.issued2018-07-05
dc.description.resumoThere are scarce data about clinical presentation and outcomes of posttransplant membranous nephropathy (MN), and few reports include a large number of patients. This was a retrospective cohort including adult patients with posttransplant MN transplanted between 1983 and 2015 in a single center (n=41). Only patients with histological diagnosis of MN in kidney grafts were included. Clinical and laboratory presentation, histological findings, treatment, and outcomes were detailed. Patients were predominantly male (58.5%), with a mean age of 49.4 ± 13.2 years; 15 were considered as recurrent primary MN; 3 were class V lupus nephritis; 14 were considered as de novo cases, 7 secondary and 7 primary MN; and 9 cases were considered primary but it was not possible to distinguish between de novo MN and recurrence. Main clinical presentations were proteinuria (75.6%) and graft dysfunction (34.1%). Most patients with primary recurrent and de novo primary MN were submitted to changes in maintenance immunosuppressive regimen, but no standard strategy was identified; 31 patients presented partial or complete remission, and glomerulopathy appeared not to impact graft and patient survival.pt_BR
dc.identifier.citationSILVA, Artur Quintiliano Bezerra da; et al. Clinical Presentation, Outcomes, and Treatment of Membranous Nephropathy after Transplantation. International Journal Of Nephrology, [S.L.], v. 2018, p. 1-6, 5 jul. 2018. Hindawi Limited. http://dx.doi.org/10.1155/2018/3720591. Acesso em: 19 maio 2022.pt_BR
dc.identifier.doihttps://doi.org/10.1155/2018/3720591
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/52490
dc.languageenpt_BR
dc.publisherInternational Journal Of Nephrologypt_BR
dc.subjectmembranous nephropathypt_BR
dc.subjecttransplantationpt_BR
dc.subjectposttransplantpt_BR
dc.titleClinical presentation, outcomes, and treatment of membranous nephropathy after transplantationpt_BR
dc.typearticlept_BR

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