Recurrent neural network modeling applied to expanded bed adsorption chromatography of chitosanases produced by Paenibacillus ehimensis

dc.contributor.authorSouza, Domingos Fabiano de Santana
dc.contributor.authorPadilha, Carlos Eduardo de Araújo
dc.contributor.authorPadilha, Carlos Alberto de Araújo
dc.contributor.authorOliveira, Jackson Araújo de
dc.contributor.authorMacedo, Gorete Ribeiro de
dc.contributor.authorSantos, Everaldo Silvino dos
dc.date.accessioned2021-12-06T18:18:18Z
dc.date.available2021-12-06T18:18:18Z
dc.date.issued2017-01
dc.description.resumoNonlinear autoregressive networks with external input (NARX) and multilayer perceptron (MLP) has been used to predict the activity and protein content for flow-through, washing and elution steps during expanded bed adsorption chromatography of chitosanases produced by Paenibacillus ehimensis. Bed expansion as well as the influence of particulatecontaining feedstock study showed a stable bed operation without significant impact on the yield as well as purification factor when the cells were fed to the column. Also, NARXs showed a better performance to predict the chitosanolytic activity as well as total protein than MLPspt_BR
dc.identifier.citationPADILHA, Carlos Eduardo de Araújo; PADILHA, Carlos Alberto de Araújo; SOUZA, Domingos Fabiano de Santana; OLIVEIRA, Jackson Araújo de; MACEDO, Gorete Ribeiro de; SANTOS, Everaldo Silvino dos. Recurrent neural network modeling applied to expanded bed adsorption chromatography of chitosanases produced by Paenibacillus ehimensis. Chemical Engineering Research And Design, [S.L.], v. 117, p. 24-33, jan. 2017. Elsevier BV. http://dx.doi.org/10.1016/j.cherd.2016.09.022. Disponível em: https://www.sciencedirect.com/science/article/pii/S0263876216303070?via%3Dihub. Acesso em: 05 nov. 2021.pt_BR
dc.identifier.doi10.1016/j.cherd.2016.09.022
dc.identifier.issn0263-8762
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/45192
dc.languageenpt_BR
dc.publisherElsevierpt_BR
dc.subjectAdsorptionpt_BR
dc.subjectDownstream processingpt_BR
dc.subjectEnzyme activitypt_BR
dc.subjectChitosanasespt_BR
dc.subjectModelingpt_BR
dc.subjectNARXpt_BR
dc.titleRecurrent neural network modeling applied to expanded bed adsorption chromatography of chitosanases produced by Paenibacillus ehimensispt_BR
dc.typearticlept_BR

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