Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms

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dc.contributor.authorEngelberth, Rovena C. G. J.
dc.contributor.authorPontes, André L. Bezerra de
dc.contributor.authorFiuza, Felipe Porto
dc.contributor.authorSilva, Kayo D. de Azevedo
dc.contributor.authorResende, Nayra da S.
dc.contributor.authorAzevedo, Carolina Virgínia de M.
dc.contributor.authorCosta, Miriam S. M. O.
dc.contributor.authorCavalcante, Judney C.
dc.contributor.authorNascimento Júnior, Expedito S.
dc.contributor.authorGavioli, Elaine Cristina
dc.contributor.authorCavalcante, Jeferson S.
dc.date.accessioned2018-02-05T22:02:44Z
dc.date.available2018-02-05T22:02:44Z
dc.date.issued2013
dc.description.resumoAnimals have neural structures that allow them to anticipate environmental changes and then regulate physiological and behavioral functions in response to these alterations. The suprachiasmatic nucleus of the hypothalamus (SCN) is the main circadian pacemaker in many mammalian species. This structure synchronizes the biological rhythm based on photic information that is transmitted to the SCN through the retinohypothalamic tract. The aging process changes the structural complexity of the nervous system, from individual nerve cells to global changes, including the atrophy of total gray matter. Aged animals show internal time disruptions caused by morphological and neurochemical changes in SCN components. The effects of aging on circadian rhythm range from effects on simple physiological functions to effects on complex cognitive performance, including many psychiatric disorders that influence the well-being of the elderly. In this review, we summarize the effects of aging on morphological, neurochemical, and circadian rhythmic functions coordinated by the main circadian pacemaker, the SCNpt_BR
dc.identifier.citationENGELBERTH, Rovena C. G. J. et al. Changes in the suprachiasmatic nucleus during aging: implications for biological rhythms. Psychology and Neuroscience, v. 6, p. 287-297, 2013. Disponível em:<http://doi.apa.org/fulltext/2014-01602-007.html>. Acesso em: 20 nov. 2017.pt_BR
dc.identifier.doi10.3922/j.psns.2013.3.07
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/24709
dc.languageengpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectSuprachiasmatic nucleuspt_BR
dc.subjectAgingpt_BR
dc.subjectMorphologicalpt_BR
dc.subjectCircadian rhythmspt_BR
dc.titleChanges in the suprachiasmatic nucleus during aging: implications for biological rhythmspt_BR
dc.typearticlept_BR

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