Dose-dependent effects of alcohol on seeking behavior and memory in the fish betta splendens

Página do item simplificado Estatísticas
dc.contributor.authorLuchiari, Ana Carolina
dc.contributor.authorChacon, Diana M.
dc.contributor.authorOliveira, Jéssica J.
dc.date.accessioned2018-01-22T19:20:35Z
dc.date.available2018-01-22T19:20:35Z
dc.date.issued2015
dc.description.resumoThe present study tested the effects of alcohol on seeking behavior and memory in the Siamese fighting fish Betta splendens. We tested behavior using 5 alcohol concentrations: .00%, .10%, .25%, 1.00%, and 1.50% (vol/vol%). Drug seeking was tested using a conditioned place preference (CPP) paradigm, with a single 20-min exposure to alcohol. The effect of alcohol on memory was tested using a T-maze protocol with acute (20 min/day for 5 days) and chronic (20 min/day for 20 days) alcohol exposure and after alcohol withdrawal (20 min/day alcohol exposure for 15 days water exposure). In the CPP test, the higher acute alcohol doses (1.00 and 1.50%) induced seeking behavior, but the lower (.10%) and medium (.25%) doses did not. When the fish were tested after 37 days of alcohol exposure, the higher-dose groups still exhibited seeking behavior, indicating that these doses may have caused drug addiction. In the memory test, we observed a dose-dependent pattern with both the acute and chronic treatments. High alcohol doses (1.00 and 1.50%) impaired memory, and low alcohol doses (.10%) caused an anticipatory response. The withdrawal group did not exhibit differences in memory, suggesting some capacity for recovery. The low alcohol doses did not impair memory or cause drug seeking, whereas the high doses affected memory and caused prolonged seeking behavior. Therefore, a dual effect of alcohol was corroborated by our data, and Betta splendens may be an adequate animal model for high-throughput screening with alcoholpt_BR
dc.identifier.citationLUCHIARI, Ana Carolina; CHACON, Diana M.; OLIVEIRA, Jéssica J. Dose-dependent effects of alcohol on seeking behavior and memory in the fish betta splendens. Psychology and Neuroscience, v. 8, p. 143-154, 2015. Disponível em:<http://doi.apa.org/fulltext/2015-12673-007.html>. Acesso em: 17 out. 2017.pt_BR
dc.identifier.doi10.1037/h0101024
dc.identifier.issn1984-3054
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/24631
dc.languageengpt_BR
dc.publisherAmerican Psychological Associationpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAbstinencept_BR
dc.subjectSeeking behaviorpt_BR
dc.subjectTolerancept_BR
dc.subjectBetta splendenspt_BR
dc.titleDose-dependent effects of alcohol on seeking behavior and memory in the fish betta splendenspt_BR
dc.typearticlept_BR

Arquivos

Pacote Original

Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
DoseDependentEffects_Luchiari_2015.pdf
Tamanho:
197.07 KB
Formato:
Adobe Portable Document Format
Nenhuma Miniatura disponível
Baixar

Licença do Pacote

Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Nenhuma Miniatura disponível
Baixar

Coleções

CB - DBIO - Artigos publicados em periódicos
Repositório Institucional - UFRN Campus Universitário Lagoa NovaCEP 59078-970 Caixa postal 1524 Natal/RN - BrasilUniversidade Federal do Rio Grande do Norte© Copyright 2025. Todos os direitos reservados.
Contato+55 (84) 3342-2260 - R232Setor de Repositórios Digitaisrepositorio@bczm.ufrn.br
DSpaceIBICT
OasisBR
LAReferencia
Customizado pela CAT - BCZM