Evolução temporal de exames bioquímicos em mulheres privadas de liberdade

Abstract

Objective: To investigate the evolution of biochemical parameters in incarcerated women. Methods: An observational prospective study involving the entire incarcerated female population in a closed regime in Natal, Rio Grande do Norte, Brazil. Biochemical tests (fasting blood glucose, total cholesterol, triglycerides, LDL-c, HDL-c, non-HDL-c) performed in the years 2012 (n = 180) and 2015 (n = 89) were compared using the Mann-Whitney, Wilcoxon and Chi-squared tests. Results: There was a high prevalence of low HDL-c, high Non-HDL-c and isolated hypertriglyceridemia in both years of the study. After three years of incarceration, the cohort of inmates showed an increase in fasting blood glucose concentrations (62.2mg/dL to 87.9mg/dL, p<0.001), total cholesterol (163.3mg/dL to 184.9mg/dL, p = 0.007), non-HDL-c (120.8mg/dL to 138.2mg/dL, p = 0.023), triglycerides (96.7mg/dL to 150.2mg/dL, p = 0.024) and HDL-c (42.5mg/dL to 46.7mg/dL, p = 0.012). Conclusion: Important biochemical changes occurred during incarceration which may favor development and worsening of chronic non-communicable diseases, highlighting the need to intensify health actions in the prison environment.