Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti

Ferreiro, Dardo Nahuel; Conde Ocazionez, Sergio Andrés; Patriota, João Henrique Nascimento; Souza, Luã Carlos de; Oliveira, Moacir Franco de; Wolf, Fred; Schmidt, Kerstin Erika

Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti

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dc.contributor.author	Ferreiro, Dardo Nahuel
dc.contributor.author	Conde Ocazionez, Sergio Andrés
dc.contributor.author	Patriota, João Henrique Nascimento
dc.contributor.author	Souza, Luã Carlos de
dc.contributor.author	Oliveira, Moacir Franco de
dc.contributor.author	Wolf, Fred
dc.contributor.author	Schmidt, Kerstin Erika
dc.date.accessioned	2020-12-14T16:42:36Z
dc.date.available	2020-12-14T16:42:36Z
dc.date.issued	2020-11-30
dc.description.resumo	All rodents investigated so far possess orientation-selective neurons in the primary visual cortex (V1) but – in contrast to carnivores and primates – no evidence of periodic maps with pinwheel-like structures. Theoretical studies debating whether phylogeny or universal principles determine development of pinwheels point to V1 size as a critical constraint. Thus, we set out to study maps of agouti, a big diurnal rodent with a V1 size comparable to cats'. In electrophysiology, we detected interspersed orientation and direction-selective neurons with a bias for horizontal contours, corroborated by homogeneous activation in optical imaging. Compatible with spatial clustering at short distance, nearby neurons tended to exhibit similar orientation preference. Our results argue against V1 size as a key parameter in determining the presence of periodic orientation maps. They are consistent with a phylogenetic influence on the map layout and development, potentially reflecting distinct retinal traits or interspecies differences in cortical circuitry	pt_BR
dc.identifier.citation	FERREIRO, Dardo N.; CONDE-OCAZIONEZ, Sergio A.; PATRIOTA, João H.N.; SOUZA, Luã C.; OLIVEIRA, Moacir F.; WOLF, Fred; SCHMIDT, Kerstin E. Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti. Iscience, [S. l.], v. 24, n. 1, p. 101882, jan. 2021. Doi: http://dx.doi.org/10.1016/j.isci.2020.101882. Disponível em: https://www.cell.com/iscience/fulltext/S2589-0042(20)31079-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004220310798%3Fshowall%3Dtrue. Acesso em: 14 dez. 2020.	pt_BR
dc.identifier.doi	https://doi.org/10.1016/j.isci.2020.101882
dc.identifier.uri	https://repositorio.ufrn.br/handle/123456789/30969
dc.language	en	pt_BR
dc.publisher	Elsevier	pt_BR
dc.rights	Attribution-NonCommercial-NoDerivs 3.0 Brazil	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/br/	*
dc.subject	Primary visual cortex (V1)	pt_BR
dc.subject	Agouti	pt_BR
dc.subject	Cuniculidae	pt_BR
dc.subject	Optical imaging	pt_BR
dc.subject	Orientation, spatial	pt_BR
dc.subject	Sensory Neuroscience	pt_BR
dc.title	Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti	pt_BR
dc.type	article	pt_BR