Effect of end-stage renal disease and diabetes on zinc and copper status

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dc.contributor.authorAlmeida, José Bruno de
dc.contributor.authorBatista, Maria Nazaré
dc.contributor.authorCuppari, Lílian
dc.contributor.authorPedrosa, Lucia de Fátima Campos
dc.contributor.authorAlmeida, Maria das Graças
dc.contributor.authorMedeiros, Anna Cecília Queiroz de
dc.contributor.authorCanziani, Maria Eugiènia F.
dc.date.accessioned2023-08-03T18:21:47Z
dc.date.available2023-08-03T18:21:47Z
dc.date.issued2006
dc.description.resumoThe aim of this study was to compare the nutritional status of zinc and copper in patients with and without diabetes submitted to chronic hemodialysis. Thirty-three patients with type 2 diabetes (DM group), 30 nondiabetic patients (NDM group), and 20 healthy individuals (control group) were studied. Plasma, erythrocyte, and urinary zinc and plasma copper were obtained from atomic absorption spectrophotometry and ceruloplasmin by immunonephelometry. The anthropometric parameters were similar among the groups. Plasma zinc was lower and erythrocyte zinc was higher in the DM and NDM groups in relation to the control group. No difference in urinary zinc was observed comparing the groups. Plasma copper was higher in the DM group when compared to the NDM and control groups. Ceruloplasmin was similar in the three groups. Serum urea was a positive independent determinant of plasma zinc concentrations. The determinants of erythrocyte zinc were MAMC midarm nuscle circumference and Kt/V dialysis adequacy. The determinants of plasma copper concentration were serum creatinine and serum glucose. The results of this study demonstrate an alteration in the distribution of zinc of patients with chronic kidney disease (CKD) independently of the presence of DM. Also, the status of copper seems not to be influenced by CKD, but only by the metabolic derangements associated with diabetes.pt_BR
dc.identifier.citationBATISTA, Maria Nazaré; CUPPARI, Lílian; PEDROSA, Lucia de Fátima Campos; ALMEIDA, Maria das Graças; ALMEIDA, José Bruno de; MEDEIROS, Anna Cecília Queiroz de; CANZIANI, Maria Eugiènia F.. Effect of End-Stage Renal Disease and Diabetes on Zinc and Copper Status. Biological Trace Element Research, [S.L.], v. 112, n. 1, p. 1-12, 2006. Springer Science and Business Media LLC. http://dx.doi.org/10.1385/bter:112:1:1. Disponível em: https://link.springer.com/article/10.1385/BTER:112:1:1. Acesso em: 28 jul. 2023.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1385/bter:112:1:1
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/54369
dc.languageenpt_BR
dc.publisherSpringerpt_BR
dc.subjectzincpt_BR
dc.subjectcopperpt_BR
dc.subjectchronic kidney diseasept_BR
dc.subjecthemodialysispt_BR
dc.subjectdiabetespt_BR
dc.titleEffect of end-stage renal disease and diabetes on zinc and copper statuspt_BR
dc.typearticlept_BR

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