Serum zinc reference intervals and its relationship with dietary, functional, and biochemical indicators in 6- to 9-year-old healthychildren

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dc.contributor.authorLopes, Márcia Marília Gomes
dc.contributor.authorAlves, Camila Xavier
dc.contributor.authorBrito, Naira Josele Neves de
dc.contributor.authorVermeulen, Karina Marques
dc.contributor.authorFrança, Mardone Cavalcante
dc.contributor.authorBruno, Selma Sousa
dc.contributor.authorAlmeida, Maria das Graças
dc.contributor.authorBrandão Neto, José
dc.contributor.authorIDhttps://orcid.org/0000-0002-0011-576Xpt_BR
dc.date.accessioned2025-02-27T19:16:33Z
dc.date.available2025-02-27T19:16:33Z
dc.date.issued2016
dc.description.resumoBackground: Zinc is an important cause of morbidity, particularly among young children. The dietary,functional, and biochemical indicators should be used to assess zinc status and to indicate the need for zincinterventions.Objective: The purpose of this study was to determine the zinc status and reference intervals for serum zincconcentration considering dietary, functional, and biochemical indicators in apparently healthy children inthe Northeast Region of Brazil.Design: The cross-sectional study included 131 healthy children: 72 girls and 59 boys, aged between 6 and9 years. Anthropometric assessment was made by body mass index (BMI) and age; dietary assessment byprospective 3-day food register, and an evaluation of total proteins was performed. Zinc in the serum sampleswas analyzed in triplicate in the same assay flame, using atomic absorption spectrophotometry.Results: With respect to dietary assessment, only the intake of fiber and calcium was below the re-commendations by age and gender. All subjects were eutrophic according to BMI and age classification. Zincintake correlated with energy (p 0.0019), protein (p 0.0054), fat (pB0.0001), carbohydrate (p 0.0305),fiber (p 0.0465), calcium (p 0.0006), and iron (p 0.0003) intakes. Serum zinc correlated with protein intake(p 0.0145) and serum albumin (p 0.0141), globulin (p 0.0041), and albumin/globulin ratio (p 0.0043).Biochemical parameters were all within the normal reference range. Reference intervals for basal serum zincconcentration were 0.70 1.14mg/mL in boys, 0.73 1.17mg/mL in girls, and 0.72 1.15mg/mL in the totalpopulation.Conclusions: This study presents pediatric reference intervals for serum zinc concentration, consideringdietary, functional, and biochemical indicators, which are useful to establish the zinc status in specific groups.In this regard, there are few studies in the literature conducted under these conditions, which make it aninnovative methodology.pt_BR
dc.identifier.citationALVES, Camila Xavier; BRITO, Naira Josele Neves de; VERMEULEN, Karina Marques; LOPES, Márcia Marília Gomes Dantas; FRANÇA, Mardone Cavalcante; BRUNO, Selma Sousa; ALMEIDA, Maria das Graças; BRANDÃO NETO, José. Serum zinc reference intervals and its relationship with dietary, functional, and biochemical indicators in 6- to 9-year-old healthy children. Food & Nutrition Research, [S.l.], v. 60, n. 1, p. 1-8, jan. 2016. DOI: 10.3402/fnr.v60.30157. Disponível em: https://foodandnutritionresearch.net/index.php/fnr/article/view/1027. Acesso em: 11 jul. 2024.pt_BR
dc.identifier.doihttp://dx.doi.org/10.3402/fnr.v60.30157
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/62869
dc.languageenpt_BR
dc.publisherFood & Nutrition Researchpt_BR
dc.rightsAttribution 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/br/*
dc.subjectZinc statuspt_BR
dc.subjectReference intervalpt_BR
dc.subjectBiochemical indicatorspt_BR
dc.subjectDietary indicatorspt_BR
dc.subjectFunctional indicatorspt_BR
dc.subjectYoung childrenpt_BR
dc.titleSerum zinc reference intervals and its relationship with dietary, functional, and biochemical indicators in 6- to 9-year-old healthychildrenpt_BR
dc.typearticlept_BR

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