Vitamin E levels in preterm and full-term nfants: a systematic review

dc.contributor.authorRibeiro, Karla Danielly da Silva
dc.contributor.authorAssunção, Débora Gabriela Fernandes
dc.contributor.authorSilva, Lorena Thalia Pereira da
dc.contributor.authorCamargo, Juliana Dantas de Araújo Santos
dc.contributor.authorCobucci, Ricardo Ney
dc.contributor.authorRibeiro, Karla Danielly da Silva
dc.contributor.authorIDhttps://orcid.org/0000-0002-2251-5967pt_BR
dc.date.accessioned2024-11-26T20:41:48Z
dc.date.available2024-11-26T20:41:48Z
dc.date.issued2022
dc.description.resumoVitamin E deficiency (VED) is associated with clinical repercussions in preterm newborns (PTN), but low levels are also found in full-term newborns (TN). As this inadequacy can compromise neurogenesis in childhood, studies are needed to assess whether there is a difference in vitamin E status among newborns according to gestational age to provide support for neonatal monitoring protocols. This systematic review presents a synthesis of the available information on the vitamin E status among PTN and TN. The review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Observational studies that evaluated alpha- tocopherol levels were searched in the databases reported in the protocol registered in PROSPERO (CRD42021165152). The Newcastle–Ottawa Scale was used to assess the methodological quality. Overall, 1809 articles were retrieved; 10 were included in the systematic review. In the PTN, the alpha-tocopherol levels ranged from 3.9 to 8.5 mmol/L, while in TN, they were 4.9 to 14.9 mmol/L, and VED ranged from 19% to 100% in newborns. Despite substantial heterogeneity in research methodology and VED classification, the results suggest that the alpha-tocopherol levels among preterm and full-term newborns is below the recommended levels. Our findings demonstrate that further investigations are needed to standardize this classification and to monitor vitamin E status in birth and postnatal with adequate bias control.pt_BR
dc.identifier.citationASSUNÇAO, Débora Gabriela Fernandes; SILVA, Lorena Thalia Pereira da; CAMARGO, Juliana Dantas de Araújo Santos; COBUCCI, Ricardo Ney; RIBEIRO, Karla Danielly da Silva.Vitamin E Levels in preterm and Full-Term Infants: A Systematic Review. Nutrients, v. 14, n. 11, p. 2257, 2022. DOI: http://dx.doi.org/10.3390/nu14112257. Disponível em: https://www.mdpi.com/2072-6643/14/11/2257. Acesso em: 4 out. 2024.pt_BR
dc.identifier.issn2072-6643
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/60683
dc.languageenpt_BR
dc.publisherNutrientspt_BR
dc.rightsAttribution 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/br/*
dc.subjectAlpha-Tocopherolpt_BR
dc.subjectVitamin E deficiency;pt_BR
dc.subjectNeonatept_BR
dc.subjectLaborpt_BR
dc.titleVitamin E levels in preterm and full-term nfants: a systematic reviewpt_BR
dc.typearticlept_BR

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