Lifestyle and family history influence cancer prognosis in Brazilian individuals

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dc.contributor.authorAraújo, Aurigena Antunes de
dc.contributor.authorAraújo Jr, Raimundo F.
dc.contributor.authorLira, George A.
dc.contributor.authorGuedes, Hugo G.
dc.contributor.authorCardoso, Marília A.
dc.contributor.authorCavalcante, Francisco J.
dc.contributor.authorAraújo, Ana Lucia M.
dc.contributor.authorRamos, Carlos César O.
dc.date.accessioned2018-06-16T11:31:58Z
dc.date.available2018-06-16T11:31:58Z
dc.date.issued2013
dc.description.resumoThe aim of this research was to study prognostic parameters of CRC by analyzing clinical and pathological variables associated with cancer patients at a northeastern Brazilian Hospital. This was a retrospective study evaluating CRC-diagnosed patients across a 10-year period (1995–2005) at Dr. Luiz Antônio Hospital in Natal, RN, Brazil. Data were collected from patients’ medical files. A total of 358 patients were included over the 10-year period. The average age at diagnosis was 58.8 years (S.D. = 15.26), 48.3% of the patients were males and 51.7% were females. Alcohol consumption significantly increased the chance of dying (p < 0.023) from colorectal cancer; this increased risk of death was approximately 71%, compared to 52.2% of the non-alcoholics. In addition, tobacco increased the chance of developing high TNM stage tumors (level III, IV; p < 0.001). Another risk factor for increased mortality was a family history for colorectal cancer (p < 0.002). Our analysis found that patients with an unhealthy lifestyle and/or family history of colorectal cancer were more likely to develop advanced stage colorectal cancer and to have a poor disease prognosis compared to patients with healthy lifestyle and/or sporadic colorectal cancer. These data suggest that a mass screening program should be implemented in northeastern Brazil in order to better prevent and treat colorectal cancer.pt_BR
dc.identifier.citationARAÚJO, Aurigena Antunes de et al. Lifestyle and family history influence cancer prognosis in Brazilian individuals. Pathology, Research and Practice, v. 209, p. 753-757, 2013. Disponível em: <https://www.sciencedirect.com/science/article/pii/S0344033813002112>. Acesso em: 14 mar. 2018.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.prp.2013.08.007
dc.identifier.issn1618-0631
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/25414
dc.languageporpt_BR
dc.publisherElsevierpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectColorectal cancerpt_BR
dc.subjectBrazilpt_BR
dc.subjectSurvivalpt_BR
dc.subjectNeoplasm by sitept_BR
dc.subjectPublic healthpt_BR
dc.titleLifestyle and family history influence cancer prognosis in Brazilian individualspt_BR
dc.typearticlept_BR

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