Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain

Tort, Adriano Bretanha Lopes; Ponsel, Simon; Jessberger, Jakob; Yanovsky, Yevgenij; Brankačk, Jurij; Draguhn, Andreas

Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain

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dc.contributor.author	Tort, Adriano Bretanha Lopes
dc.contributor.author	Ponsel, Simon
dc.contributor.author	Jessberger, Jakob
dc.contributor.author	Yanovsky, Yevgenij
dc.contributor.author	Brankačk, Jurij
dc.contributor.author	Draguhn, Andreas
dc.date.accessioned	2018-04-26T14:16:38Z
dc.date.available	2018-04-26T14:16:38Z
dc.date.issued	2018-04-24
dc.description.resumo	Slow brain oscillations are usually coherent over long distances and thought to link distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow rhythms. However, mice often breathe at theta frequency, and we recently reported that nasal respiration leads to local field potential (LFP) oscillations that are independent of theta. Namely, we showed respiration-coupled oscillations in the hippocampus, prelimbic cortex, and parietal cortex, suggesting that respiration could impose a global brain rhythm. Here we extend these findings by analyzing LFPs from 15 brain regions recorded simultaneously with respiration during exploration and REM sleep. We find that respiration-coupled oscillations can be detected in parallel with theta in several neocortical regions, from prefrontal to visual areas, and also in subcortical structures such as the thalamus, amygdala and ventral hippocampus. They might have escaped attention in previous studies due to the absence of respiration monitoring, the similarity with theta oscillations, and the highly variable peak frequency. We hypothesize that respiration-coupled oscillations constitute a global brain rhythm suited to entrain distributed networks into a common regime. However, whether their widespread presence reflects local network activity or is due to volume conduction remains to be determined.	pt_BR
dc.identifier.citation	TORT, A. B. L. et al. Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain. [s.l.], Scientific Reports, v. 8, n. 6432, abr./2018.	pt_BR
dc.identifier.doi	10.1038/s41598-018-24629-z
dc.identifier.uri	https://repositorio.ufrn.br/jspui/handle/123456789/25084
dc.language	eng	pt_BR
dc.rights	Acesso Aberto	pt_BR
dc.subject	oscillations respiration-coupled	pt_BR
dc.subject	theta	pt_BR
dc.subject	local field potential	pt_BR
dc.subject	hippocampus	pt_BR
dc.title	Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain	pt_BR
dc.type	article	pt_BR