Adhesion prevention in reabsorbable polyethylene glycol hydrogel (Coseal®) coated polypropylene mesh in rabbits

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dc.contributor.authorQuinino, Reynaldo Martins e
dc.contributor.authorAraújo Filho, Irami
dc.contributor.authorLima, Francisco Piganataro
dc.contributor.authorBarbosa, André Luís Costa
dc.contributor.authorMaia, Tatiana de Carvalho
dc.contributor.authorGoldenberg, Alberto
dc.contributor.authorIDhttps://orcid.org/0000-0002-4284-2543pt_BR
dc.date.accessioned2023-07-10T20:08:29Z
dc.date.available2023-07-10T20:08:29Z
dc.date.issued2013-12
dc.description.resumoPurpose: To evaluate of postoperative adhesion prevention and inflammatory response to polypropylene mesh, coated with reabsorbable hydrogel of polyethylene glycol (Coseal®) in contact with small bowel in an experimental model in rabbits. Methods: Twenty female rabbits underwent laparotomy to implant two polypropylene meshes, 2x1cm, in the right and left flanks. The right mesh was protected with Coseal® spray (Group 1) and the left mesh received no treatment after implantation (Group 2). Thirty days after implantation, the rabbits underwent laparoscopy for adhesion analysis; the prosthesis were removed en bloc with the adjacent tissue for microscopic analysis of inflammation. Statistical analysis used the Mann-Whitney test. RESULTS: There was adhesion formation in five meshes (36%) from Group 1 and in 14 meshes (100%) from Group 2, with statistical significance (p<0.01). There were no differences in the inflammatory response, fibrosis, foreign body reaction, presence of collagen and type of inflammatory cells between the two groups. Conclusion: Polypropylene mesh coated with Coseal® showed a significantly lower rate of adhesion formation when compared with uncoated meshes, without interfering with inflammatory response.pt_BR
dc.identifier.citationQUININO, Reynaldo Martins e; ARAUJO FILHO, Irami; LIMA, Francisco Piganataro; BARBOSA, André Luís Costa; MAIA, Tatiana de Carvalho; GOLDENBERG, Alberto. Adhesion prevention in reabsorbable polyethylene glycol hydrogel (Coseal®) coated polypropylene mesh in rabbits. Acta Cirurgica Brasileira, [S.L.], v. 28, n. 12, p. 807-814, dez. 2013. FapUNIFESP (SciELO). http://dx.doi.org/10.1590/s0102-86502013001200001. Disponível em: https://www.scielo.br/j/acb/a/hx8z6FfCCxdmB9d7tfKTLzg/?lang=en. Acesso em: 10 jul. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1590/S0102-86502013001200001
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/53204
dc.languageenpt_BR
dc.publisherActa Cirurgica Brasileirapt_BR
dc.rightsAttribution-NonCommercial 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/br/*
dc.subjecttissue adhesionspt_BR
dc.subjectpolyethylene glycolspt_BR
dc.subjectpolypropylenespt_BR
dc.subjectrabbits.pt_BR
dc.titleAdhesion prevention in reabsorbable polyethylene glycol hydrogel (Coseal®) coated polypropylene mesh in rabbitspt_BR
dc.typearticlept_BR

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