Blueberry polyphenol-protein food ingredients: the impact of spray drying on the in vitro antioxidant activity, anti-inflammatory markers, glucose metabolism and fibroblast migration
| dc.contributor.author | Hoskin, Roberta Targino | |
| dc.contributor.author | Xiong, Jia | |
| dc.contributor.author | Esposito, Debora Araújo | |
| dc.contributor.author | Lila, Mary Ann | |
| dc.date.accessioned | 2021-12-15T14:26:08Z | |
| dc.date.available | 2021-12-15T14:26:08Z | |
| dc.date.issued | 2019-05 | |
| dc.description.resumo | Wild blueberry pomace extract complexed with wheat or chickpea flour or soy protein isolate produced spray dried and freeze-dried polyphenol-protein particles. To evaluate the impact of spray drying on the biological activity of these food ingredients in vitro antioxidant and anti-inflammatory activities, regulation of glucose metabolism and ability to stimulate fibroblast migration were tested. Extracts from polyphenol-protein particles significantly decreased reactive oxygen species (ROS) production and down-regulated the gene expression of inflammation markers (COX-2 and IL-1β). Milder suppression of nitric oxide production and inducible nitric oxide synthase (iNOS) gene expression was evident. The extracts significantly inhibited phosphoenolpyruvate carboxykinase (PEPCK) and accelerated fibroblast cell migration up to 3-fold after 24 h. Complexed polyphenols retained their structural integrity and bioactive potency for both lyophilized and spray dried treatments. The data suggests that spray drying is a convenient and cost-effective technique to produce blueberry-polyphenol food ingredients with preserved phytochemicals with biological activities | pt_BR |
| dc.identifier.citation | Hoskin, Roberta Targino; XIONG, Jia; ESPOSITO, Debora Araújo; LILA, Mary Ann. Blueberry polyphenol-protein food ingredients: The impact of spray drying on the in vitro antioxidant activity, anti-inflammatory markers, glucose metabolism and fibroblast migration. FOOD CHEMISTRY, v. 280, p. 187-194, 2019. Disponível em: https://www.sciencedirect.com/science/article/abs/pii/S0308814618321502?via%3Dihub. Acesso em: 04 nov. 2021. https://doi.org/10.1016/j.foodchem.2018.12.046 | pt_BR |
| dc.identifier.doi | 10.1016/j.foodchem.2018.12.046 | |
| dc.identifier.issn | 0308-8146 | |
| dc.identifier.uri | https://repositorio.ufrn.br/handle/123456789/45377 | |
| dc.language | en | pt_BR |
| dc.publisher | Elsevier | pt_BR |
| dc.subject | Berries | pt_BR |
| dc.subject | By-products | pt_BR |
| dc.subject | Drying | pt_BR |
| dc.subject | Inflammation | pt_BR |
| dc.subject | Phytochemicals | pt_BR |
| dc.title | Blueberry polyphenol-protein food ingredients: the impact of spray drying on the in vitro antioxidant activity, anti-inflammatory markers, glucose metabolism and fibroblast migration | pt_BR |
| dc.type | article | pt_BR |
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